JSUM ultrasound elastography practice guidelines: Liver

Masatoshi Kudo, Tsuyoshi Shiina, Fuminori Moriyasu, Hiroko Iijima, Ryosuke Tateishi, Norihisa Yada, Kenji Fujimoto, Hiroyasu Morikawa, Masashi Hirooka, Yasukiyo Sumino, Takashi Kumada

Research output: Contribution to journalReview articlepeer-review

68 Citations (Scopus)

Abstract

In diffuse liver disease, it is extremely important to make an accurate diagnosis of liver fibrosis prior to determining indications for therapy or predicting treatment outcome and malignant potential. Although liver biopsy has long been the gold standard in the diagnosis of liver fibrosis, it is still an invasive method. In addition, the sampling error is an intrinsic problem of liver biopsy. Non-invasive serological methods for the diagnosis of liver fibrosis can be affected by factors unrelated to the liver. Recently, after the introduction of FibroScan, it became possible to measure liver fibrosis directly and non-invasively by elastography, which has attracted attention as a non-invasive imaging diagnostic tool for liver fibrosis. In addition, real-time tissue elastography is currently being used to conduct clinical trials at many institutions. Moreover, virtual touch quantification enables the observation of liver stiffness at any location by simply observing B-mode images. Furthermore, the recently developed ShearWave elastography visualizes liver stiffness on a color map. Elastography is thought to be useful for all types of diffuse liver diseases. Because of its association with portal hypertension and liver carcinogenesis, elastography is expected to function as a novel prognostic tool for liver disease. Although various elastographic devices have been developed by multiple companies, each device has its own measurement principle, method, and outcome, creating confusion in clinical settings. Therefore, it is extremely important to understand the characteristics of each device in advance. The objective of this guideline, which describes the characteristics of each device based on the latest knowledge, is for all users to be able to make the correct diagnosis of hepatic fibrosis by ultrasound elastography.

Original languageEnglish
Pages (from-to)325-357
Number of pages33
JournalJournal of Medical Ultrasonics
Volume40
Issue number4
DOIs
Publication statusPublished - 2013 Oct
Externally publishedYes

Keywords

  • Elasticity
  • Elastography
  • Liver fibrosis
  • Shear wave
  • Stiffness
  • Strain

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint

Dive into the research topics of 'JSUM ultrasound elastography practice guidelines: Liver'. Together they form a unique fingerprint.

Cite this