Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA

Kazunari Matsumura, Masayuki Endo, Makoto Komiyama

Research output: Contribution to journalArticlepeer-review

128 Citations (Scopus)

Abstract

Iminodiacetate complexes of lanthanide(III) ions (lutetium, europium, thulium and lanthanum), attached to the 5′-end of a 15-mer DNA, hydrolyse a 39-mer RNA selectively at the 3′-side of its 15-mer sequence, which is complementary with the DNA.

Original languageEnglish
Pages (from-to)2019-2020
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number17
DOIs
Publication statusPublished - 1994 Dec 1
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

Fingerprint Dive into the research topics of 'Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA'. Together they form a unique fingerprint.

Cite this