Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA

Kazunari Matsumura, M. Endo, M. Komiyama

Research output: Contribution to journalArticle

127 Citations (Scopus)

Abstract

Iminodiacetate complexes of lanthanide(III) ions (lutetium, europium, thulium and lanthanum), attached to the 5'-end of a 15-mer DNA, hydrolyse a 39-mer RNA selectively at the 3'-side of its 15-mer-sequence, which is complementary with the DNA.

Original languageEnglish
Pages (from-to)2019-2020
Number of pages2
JournalJournal of the Chemical Society - Series Chemical Communications
Issue number17
Publication statusPublished - 1994
Externally publishedYes

Fingerprint

Lanthanoid Series Elements
Rare earth elements
RNA
Hydrolysis
Thulium
DNA
Lutetium
Europium
Lanthanum
Ions

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA. / Matsumura, Kazunari; Endo, M.; Komiyama, M.

In: Journal of the Chemical Society - Series Chemical Communications, No. 17, 1994, p. 2019-2020.

Research output: Contribution to journalArticle

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