Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA

Kazunari Matsumura; Masayuki Endo; Makoto Komiyama

doi:10.1039/C39940002019

Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA

Kazunari Matsumura, Masayuki Endo, Makoto Komiyama

Research output: Contribution to journal › Article › peer-review

131 Citations (Scopus)

Abstract

Iminodiacetate complexes of lanthanide(III) ions (lutetium, europium, thulium and lanthanum), attached to the 5′-end of a 15-mer DNA, hydrolyse a 39-mer RNA selectively at the 3′-side of its 15-mer sequence, which is complementary with the DNA.

Original language	English
Pages (from-to)	2019-2020
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	17
DOIs	https://doi.org/10.1039/C39940002019
Publication status	Published - 1994 Dec 1
Externally published	Yes

ASJC Scopus subject areas

Molecular Medicine

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10.1039/C39940002019

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title = "Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA",

abstract = "Iminodiacetate complexes of lanthanide(III) ions (lutetium, europium, thulium and lanthanum), attached to the 5′-end of a 15-mer DNA, hydrolyse a 39-mer RNA selectively at the 3′-side of its 15-mer sequence, which is complementary with the DNA.",

author = "Kazunari Matsumura and Masayuki Endo and Makoto Komiyama",

year = "1994",

month = dec,

day = "1",

doi = "10.1039/C39940002019",

language = "English",

pages = "2019--2020",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

number = "17",

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T1 - Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA

AU - Matsumura, Kazunari

AU - Endo, Masayuki

AU - Komiyama, Makoto

PY - 1994/12/1

Y1 - 1994/12/1

N2 - Iminodiacetate complexes of lanthanide(III) ions (lutetium, europium, thulium and lanthanum), attached to the 5′-end of a 15-mer DNA, hydrolyse a 39-mer RNA selectively at the 3′-side of its 15-mer sequence, which is complementary with the DNA.

AB - Iminodiacetate complexes of lanthanide(III) ions (lutetium, europium, thulium and lanthanum), attached to the 5′-end of a 15-mer DNA, hydrolyse a 39-mer RNA selectively at the 3′-side of its 15-mer sequence, which is complementary with the DNA.

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U2 - 10.1039/C39940002019

DO - 10.1039/C39940002019

M3 - Article

AN - SCOPUS:0027971137

SN - 1359-7345

SP - 2019

EP - 2020

JO - Chemical Communications

JF - Chemical Communications

IS - 17

ER -

Lanthanide complex-oligo-DNA hybrid for sequence-selective hydrolysis of RNA

Abstract

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