Laser-driven short-duration heating angioplasty

Dilatation performance in cadaver atherosclerotic femoral arteries

Natsumi Shimazaki, Sho Naruse, Tsunenori Arai, Nobuaki Imanishi, Sadakazu Aiso

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The purpose of this study was to investigate the artery dilatation performance of the short-duration heating balloon catheter in cadaver stenotic arteries. We designed a prototype short-duration heating balloon catheter that can heat artery media to around 60 °C in 15-25 s by a combination of laser-driven heat generation and continuous fluid irrigation in the balloon. We performed ex vivo short-duration heating dilatation in the cadaver atherosclerotic femoral arteries (initial percent diameter stenosis was 36-98%), with the maximum balloon temperature of 65±5 °C, laser irradiation duration of 25 s, and balloon dilatation pressure of 3.5 atm. The artery lumen configurations before and after the dilatations were assessed with a commercial IVUS system. After the short-duration heating dilatations, the percent diameter stenosis was reduced below 30% without any artery tears or dissections. We estimated that the artery media temperature was raised to around 60 °C in which plaque thickness was below 0.8 mm by a thermal conduction calculation. The estimated maximum temperature in artery adventitia and surrounding tissue was up to 45 °C. We found that the short-duration heating balloon could sufficiently dilate the cadaver stenotic arteries, without thermal injury in artery adventitia and surroundings.

Original languageEnglish
Title of host publicationPhotonic Therapeutics and Diagnostics IX
Volume8565
DOIs
Publication statusPublished - 2013 May 30
Externally publishedYes
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: 2013 Feb 22013 Feb 7

Other

OtherPhotonic Therapeutics and Diagnostics IX
CountryUnited States
CitySan Francisco, CA
Period13/2/213/2/7

Fingerprint

Balloons
arteries
Heating
balloons
heating
Lasers
lasers
Catheters
Dissection
Heat generation
Laser beam effects
Irrigation
Temperature
irrigation
dissection
lumens
Tissue
heat generation
Fluids
temperature

Keywords

  • Balloon angioplasty
  • Extracted human cadaver artery
  • Thermal angioplasty

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Shimazaki, N., Naruse, S., Arai, T., Imanishi, N., & Aiso, S. (2013). Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries. In Photonic Therapeutics and Diagnostics IX (Vol. 8565). [85654E] https://doi.org/10.1117/12.2005432

Laser-driven short-duration heating angioplasty : Dilatation performance in cadaver atherosclerotic femoral arteries. / Shimazaki, Natsumi; Naruse, Sho; Arai, Tsunenori; Imanishi, Nobuaki; Aiso, Sadakazu.

Photonic Therapeutics and Diagnostics IX. Vol. 8565 2013. 85654E.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shimazaki, N, Naruse, S, Arai, T, Imanishi, N & Aiso, S 2013, Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries. in Photonic Therapeutics and Diagnostics IX. vol. 8565, 85654E, Photonic Therapeutics and Diagnostics IX, San Francisco, CA, United States, 13/2/2. https://doi.org/10.1117/12.2005432
Shimazaki N, Naruse S, Arai T, Imanishi N, Aiso S. Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries. In Photonic Therapeutics and Diagnostics IX. Vol. 8565. 2013. 85654E https://doi.org/10.1117/12.2005432
Shimazaki, Natsumi ; Naruse, Sho ; Arai, Tsunenori ; Imanishi, Nobuaki ; Aiso, Sadakazu. / Laser-driven short-duration heating angioplasty : Dilatation performance in cadaver atherosclerotic femoral arteries. Photonic Therapeutics and Diagnostics IX. Vol. 8565 2013.
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