Light-drive biomedical micro tools and biochemical IC chips fabricated by 3D micro/nano stereolithography

Koji Ikuta, Shoji Maruo, Tadahiro Hasegawa, Suenobu Itho, Hayato Korogi, Atsushi Takahashi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

New concept of micro/nano tools working in water solutuon has been proposed by the author. A real three dimensional micro fabrication process using photo curable polymer named "micro/nano stereolithography "has been also developed by the author's group. The latest version of this process achieved 100 nm in 3D resolution and freely movable micro/nano mechanism are easily fabricated within 20 min. Nano tweezers and nano needle with two degrees of freedom were successfully fabricated without any assembly process. Cell and delicate biological materials can be remotely handled with neither any micro actuators nor lead wire. It was verified that this light-driven micro tool has precise force control with 10 FtN. These light-driven micro tools contribute to cellular biology as well as medical tools. The second application of microstereolithography is the biochemical IC chips for both micro chemical analysis and synthesis. Unlike conventional "lab. on a chip" and "micro total analysis system (micro-TAS), our biochemical IC has micro pumps and active valves in one chip. Users can construct their own micro chemical device by themselves. The advanced biochemical IC chip-set for "on chip cell-free protein synthesis" has been prototyped and verified experimentally. A luminous enzyme of fire fly so called " Luciferase" and useful bio-marker protein "GFP" were synthesized successfully. According to above results, the biomchemical IC chips will be useful to "Order-made medicine" in near future.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsY. Katagiri
Pages52-66
Number of pages15
Volume5604
DOIs
Publication statusPublished - 2004
Externally publishedYes
EventOptomechatronic Micro/Nano Components, Devices, and Systems - Philadelphia, PA, United States
Duration: 2004 Oct 272004 Oct 28

Other

OtherOptomechatronic Micro/Nano Components, Devices, and Systems
CountryUnited States
CityPhiladelphia, PA
Period04/10/2704/10/28

Fingerprint

Stereolithography
lithography
chips
Cytology
Proteins
Microfabrication
Force control
Needles
Biological materials
protein synthesis
Medicine
Fires
Actuators
Enzymes
systems analysis
Pumps
Wire
cells
chemical analysis
biology

Keywords

  • Biochemical IC
  • Light drive
  • Micro stereolithography
  • Nano manipulator
  • Optical drive

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Ikuta, K., Maruo, S., Hasegawa, T., Itho, S., Korogi, H., & Takahashi, A. (2004). Light-drive biomedical micro tools and biochemical IC chips fabricated by 3D micro/nano stereolithography. In Y. Katagiri (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 5604, pp. 52-66). [08] https://doi.org/10.1117/12.581900

Light-drive biomedical micro tools and biochemical IC chips fabricated by 3D micro/nano stereolithography. / Ikuta, Koji; Maruo, Shoji; Hasegawa, Tadahiro; Itho, Suenobu; Korogi, Hayato; Takahashi, Atsushi.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Y. Katagiri. Vol. 5604 2004. p. 52-66 08.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ikuta, K, Maruo, S, Hasegawa, T, Itho, S, Korogi, H & Takahashi, A 2004, Light-drive biomedical micro tools and biochemical IC chips fabricated by 3D micro/nano stereolithography. in Y Katagiri (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5604, 08, pp. 52-66, Optomechatronic Micro/Nano Components, Devices, and Systems, Philadelphia, PA, United States, 04/10/27. https://doi.org/10.1117/12.581900
Ikuta K, Maruo S, Hasegawa T, Itho S, Korogi H, Takahashi A. Light-drive biomedical micro tools and biochemical IC chips fabricated by 3D micro/nano stereolithography. In Katagiri Y, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 5604. 2004. p. 52-66. 08 https://doi.org/10.1117/12.581900
Ikuta, Koji ; Maruo, Shoji ; Hasegawa, Tadahiro ; Itho, Suenobu ; Korogi, Hayato ; Takahashi, Atsushi. / Light-drive biomedical micro tools and biochemical IC chips fabricated by 3D micro/nano stereolithography. Proceedings of SPIE - The International Society for Optical Engineering. editor / Y. Katagiri. Vol. 5604 2004. pp. 52-66
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