Localization of Gamma-Glutamyl Transpeptidase in the Proliferative State of Liver An Enzyme Histochemical and Immunohistochemical Study

Masahide Shiozawa, Sadakazu Aiso, Osamu Hoshiai, Hiromu Tahara, Shuji Yamashita, Kenjiro Yasuda

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The appearance and distribution of 7-glutamyl transpetidase (7-GTP) in the proliferative state of the liver were investigated by the methods of enzyme histochemistry and immunohistochemistry with monoclonal antibodies which specifically react with a heavy subunit of 7-GTP. In the fatal and neonatal liver, a positive reaction was observed along the luminal border of the interlobular bile ducts and that of the bile canaliculi in zones 1 and 2 of Rappaport. On the other hand, after partial hepatectomy, 7-GTP was localized along the luminal border of the interlobular bile ducts and that of the bile canaliculi in zone 1 of Rappaport. Both the enzyme histochemical and immunohistochemical methods yielded almost the same results for the distribution of 7-GTP.

Original languageEnglish
Pages (from-to)209-221
Number of pages13
JournalOkajimas Folia Anatomica Japonica
Volume63
Issue number4
DOIs
Publication statusPublished - 1986 Jan 1
Externally publishedYes

Keywords

  • Aging
  • Gamma-GTP
  • Hepatectomy
  • Histochemistry
  • Immunohistochemistry
  • Rat

ASJC Scopus subject areas

  • Anatomy

Cite this

Localization of Gamma-Glutamyl Transpeptidase in the Proliferative State of Liver An Enzyme Histochemical and Immunohistochemical Study. / Shiozawa, Masahide; Aiso, Sadakazu; Hoshiai, Osamu; Tahara, Hiromu; Yamashita, Shuji; Yasuda, Kenjiro.

In: Okajimas Folia Anatomica Japonica, Vol. 63, No. 4, 01.01.1986, p. 209-221.

Research output: Contribution to journalArticle

Shiozawa, Masahide ; Aiso, Sadakazu ; Hoshiai, Osamu ; Tahara, Hiromu ; Yamashita, Shuji ; Yasuda, Kenjiro. / Localization of Gamma-Glutamyl Transpeptidase in the Proliferative State of Liver An Enzyme Histochemical and Immunohistochemical Study. In: Okajimas Folia Anatomica Japonica. 1986 ; Vol. 63, No. 4. pp. 209-221.
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