Microfluidic immunoassay for alveolar cell released interleukin-8 using a braille display for computer-controlled fluid actuation

Y. Kamotani, W. Gu, N. Futai, S. Takayama

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We have developed a self-contained, connectorless, automated microfluidic immunoassay system to detect and quantify levels of Interleukin (IL)-8, an important cytokine involved in the inflammatory response. In our microfluidic system, liquid flow is controlled using the pins of a commercially available, refreshable Braille display that act as small mechanical actuators. The successful development of such a microsystem will prove beneficial in both the early diagnosis and treatment of various disease states. Integration of the microfluidic immunoassay system with cell culture can provide a novel, self-contained device to analyze the by-products of chemically stimulated cells in a controlled microenvironment.

Original languageEnglish
Title of host publicationProceedings of 2006 International Conference on Microtechnologies in Medicine and Biology
Pages49-51
Number of pages3
DOIs
Publication statusPublished - 2006 Dec 1
Externally publishedYes
Event2006 International Conference on Microtechnologies in Medicine and Biology - Okinawa, Japan
Duration: 2006 May 92006 May 12

Publication series

NameProceedings of 2006 International Conference on Microtechnologies in Medicine and Biology

Conference

Conference2006 International Conference on Microtechnologies in Medicine and Biology
Country/TerritoryJapan
CityOkinawa
Period06/5/906/5/12

Keywords

  • Bead-based immunoassay
  • Epithelial cell culture
  • Microfiuidics

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Medicine(all)

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