Microfluidic immunoassay for alveolar cell released interleukin-8 using a braille display for computer-controlled fluid actuation

Y. Kamotani, W. Gu, N. Futai, S. Takayama

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We have developed a self-contained, connectorless, automated microfluidic immunoassay system to detect and quantify levels of Interleukin (IL)-8, an important cytokine involved in the inflammatory response. In our microfluidic system, liquid flow is controlled using the pins of a commercially available, refreshable Braille display that act as small mechanical actuators. The successful development of such a microsystem will prove beneficial in both the early diagnosis and treatment of various disease states. Integration of the microfluidic immunoassay system with cell culture can provide a novel, self-contained device to analyze the by-products of chemically stimulated cells in a controlled microenvironment.

Original languageEnglish
Title of host publicationProceedings of 2006 International Conference on Microtechnologies in Medicine and Biology
Pages49-51
Number of pages3
DOIs
Publication statusPublished - 2006 Dec 1
Externally publishedYes
Event2006 International Conference on Microtechnologies in Medicine and Biology - Okinawa, Japan
Duration: 2006 May 92006 May 12

Publication series

NameProceedings of 2006 International Conference on Microtechnologies in Medicine and Biology

Conference

Conference2006 International Conference on Microtechnologies in Medicine and Biology
CountryJapan
CityOkinawa
Period06/5/906/5/12

Keywords

  • Bead-based immunoassay
  • Epithelial cell culture
  • Microfiuidics

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Medicine(all)

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