Minimally invasive needle-free bubble injector for gene therapy

Kazuki Takahashi; Shun Omi; Yoko Yamanishi

doi:10.1109/MEMSYS.2015.7051042

Minimally invasive needle-free bubble injector for gene therapy

Kazuki Takahashi, Shun Omi, Yoko Yamanishi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

We have successfully developed minimally-invasive needle-free bubble-injector designed for usage in air. The novelty is that minimally-invasiveness of injection whose resolution is less than 10 μm, and hence cellular-scale and painless injection can be obtained. The bubble-injector can be employed to any kind of materials with wide range of hardness using strong impact of cavitation. The fine adjustment of invasiveness of injection can be controlled by the number of applied electric pulses. The developed injector can be used for wide range of biomedical study, especially in gene therapy.

Original language	English
Title of host publication	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	655-657
Number of pages	3
Volume	2015-February
Edition	February
DOIs	https://doi.org/10.1109/MEMSYS.2015.7051042
Publication status	Published - 2015 Feb 26
Event	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: 2015 Jan 18 → 2015 Jan 22

Other

Other	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015
Country/Territory	Portugal
City	Estoril
Period	15/1/18 → 15/1/22

ASJC Scopus subject areas

Electrical and Electronic Engineering
Mechanical Engineering
Condensed Matter Physics
Electronic, Optical and Magnetic Materials

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10.1109/MEMSYS.2015.7051042

Cite this

Minimally invasive needle-free bubble injector for gene therapy. / Takahashi, Kazuki; Omi, Shun; Yamanishi, Yoko.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). Vol. 2015-February February. ed. Institute of Electrical and Electronics Engineers Inc., 2015. p. 655-657 7051042.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Takahashi, K, Omi, S & Yamanishi, Y 2015, Minimally invasive needle-free bubble injector for gene therapy. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). February edn, vol. 2015-February, 7051042, Institute of Electrical and Electronics Engineers Inc., pp. 655-657, 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015, Estoril, Portugal, 15/1/18. https://doi.org/10.1109/MEMSYS.2015.7051042

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AB - We have successfully developed minimally-invasive needle-free bubble-injector designed for usage in air. The novelty is that minimally-invasiveness of injection whose resolution is less than 10 μm, and hence cellular-scale and painless injection can be obtained. The bubble-injector can be employed to any kind of materials with wide range of hardness using strong impact of cavitation. The fine adjustment of invasiveness of injection can be controlled by the number of applied electric pulses. The developed injector can be used for wide range of biomedical study, especially in gene therapy.

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Minimally invasive needle-free bubble injector for gene therapy

Abstract

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