Minimally invasive needle-free bubble injector for gene therapy

Kazuki Takahashi, Shun Omi, Yoko Yamanishi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have successfully developed minimally-invasive needle-free bubble-injector designed for usage in air. The novelty is that minimally-invasiveness of injection whose resolution is less than 10 μm, and hence cellular-scale and painless injection can be obtained. The bubble-injector can be employed to any kind of materials with wide range of hardness using strong impact of cavitation. The fine adjustment of invasiveness of injection can be controlled by the number of applied electric pulses. The developed injector can be used for wide range of biomedical study, especially in gene therapy.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages655-657
Number of pages3
Volume2015-February
EditionFebruary
DOIs
Publication statusPublished - 2015 Feb 26
Event2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal
Duration: 2015 Jan 182015 Jan 22

Other

Other2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015
CountryPortugal
CityEstoril
Period15/1/1815/1/22

Fingerprint

gene therapy
Gene therapy
injectors
Cavitation
needles
Needles
bubbles
Hardness
injection
Air
electric pulses
cavitation flow
hardness
adjusting
air

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Takahashi, K., Omi, S., & Yamanishi, Y. (2015). Minimally invasive needle-free bubble injector for gene therapy. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (February ed., Vol. 2015-February, pp. 655-657). [7051042] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2015.7051042

Minimally invasive needle-free bubble injector for gene therapy. / Takahashi, Kazuki; Omi, Shun; Yamanishi, Yoko.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). Vol. 2015-February February. ed. Institute of Electrical and Electronics Engineers Inc., 2015. p. 655-657 7051042.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Takahashi, K, Omi, S & Yamanishi, Y 2015, Minimally invasive needle-free bubble injector for gene therapy. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). February edn, vol. 2015-February, 7051042, Institute of Electrical and Electronics Engineers Inc., pp. 655-657, 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015, Estoril, Portugal, 15/1/18. https://doi.org/10.1109/MEMSYS.2015.7051042
Takahashi K, Omi S, Yamanishi Y. Minimally invasive needle-free bubble injector for gene therapy. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). February ed. Vol. 2015-February. Institute of Electrical and Electronics Engineers Inc. 2015. p. 655-657. 7051042 https://doi.org/10.1109/MEMSYS.2015.7051042
Takahashi, Kazuki ; Omi, Shun ; Yamanishi, Yoko. / Minimally invasive needle-free bubble injector for gene therapy. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). Vol. 2015-February February. ed. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 655-657
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