Mouth guard type biosensor cavitous sensor for monitoring of saliva glucose with telemetry system

Takahiro Arakawa, Yusuke Kuroki, Hiroki Nitta, Koji Toma, Kohji Mitsubayashi, Shuhei Takeuchi, Toshiaki Sekita, Shunsuke Minakuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

We have developed detachable Cavitas sensors into human cavitas sites of oral cavity for non-invasive monitoring of saliva glucose. A salivary biosensor based on the integration of Pt and Ag/AgCl electrodes with an enzyme membrane on a mouth guard was developed and tested. This mouth guard type biosensor was integrated with a glucose sensor and wireless measurement system. The electrodes were formed on the mouth guard surface which made of a polyethylene terephthalate glycol (PETG). The Pt working electrode was coated with the glucose oxidase (GOD) membrane. In the investigation of in-vitro characterization, the biosensor showed excellent relationship between the output current and the glucose concentration. In artificial saliva consisting of salts and proteins, the glucose sensor exhibits high-sensitive detection in a range of 5-1000 μmol/L. We demonstrated the capability of the sensor and wireless communication module to characterize an inclusion in oral phantom that imitative structure of human oral cavity. Stable and long-term monitoring (more than 2 hours) using telemetry system was established. The mouth guard biosensor would be useful for real-time and non-invasive method as a novel health care management.

Original languageEnglish
Title of host publication2015 9th International Conference on Sensing Technology, ICST 2015
PublisherIEEE Computer Society
Pages46-49
Number of pages4
ISBN (Electronic)9781479963140
DOIs
Publication statusPublished - 2016 Mar 21
Externally publishedYes
Event9th International Conference on Sensing Technology, ICST 2015 - Auckland, New Zealand
Duration: 2015 Dec 82015 Dec 11

Publication series

NameProceedings of the International Conference on Sensing Technology, ICST
Volume2016-March
ISSN (Print)2156-8065
ISSN (Electronic)2156-8073

Other

Other9th International Conference on Sensing Technology, ICST 2015
Country/TerritoryNew Zealand
CityAuckland
Period15/12/815/12/11

Keywords

  • biosensor
  • glucose
  • glucose oxidase
  • mouth guard
  • oral cavity
  • saliva glucose

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computer Science Applications
  • Signal Processing
  • Electrical and Electronic Engineering

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