Nanometer level resolving near field optical microscope under optical feedback in the observation of a single-string deoxyribo nucleic acid

Rajagopalan Umamaheswari, Shuji Mononobe, Kenji Yoshida, Mamoru Yoshimoto, Motoichi Ohtsu

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We present the observation results of a single string deoxyribo nucleic acid (DNA) obtained by a collection mode near field optical microscope (NOM) operated under constant distance mode with the optical near field intensity as the feedback signal. The observed width of the narrowest string is around 4 nm. To our knowledge, this is not only the successful optical observation of a single string DNA by purely optical means but also under such high resolving capability. This high resolution is mainly attributed to the special care taken during the preparation of the sample and of the probe to avoid unwanted scattered light. The probe efficiently picks up the high spatial frequency component of the scattered near field and simultaneously rejects out effectively the lower spatial frequency components.

Original languageEnglish
Pages (from-to)6713-6720
Number of pages8
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Volume38
Issue number12 A
Publication statusPublished - 1999 Dec 1
Externally publishedYes

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Optical feedback
Nucleic acids
nucleic acids
optical microscopes
near fields
Microscopes
strings
probes
Feedback
preparation
high resolution

Keywords

  • Collection mode
  • Constant distance mode
  • DNA string
  • Efficient far-field rejection probe
  • Nanometer resolution
  • Near-field optical microscope
  • Optical feedback
  • Ultra-flat sapphire surface

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Nanometer level resolving near field optical microscope under optical feedback in the observation of a single-string deoxyribo nucleic acid. / Umamaheswari, Rajagopalan; Mononobe, Shuji; Yoshida, Kenji; Yoshimoto, Mamoru; Ohtsu, Motoichi.

In: Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers, Vol. 38, No. 12 A, 01.12.1999, p. 6713-6720.

Research output: Contribution to journalArticle

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