To evaluate the effectiveness of Real-time Tissue Elastography (RTE) in staging of liver fibrosis noninvasively, we performed RTE on 310 patients with chronic hepatitis C (and/or liver cirrhosis) and 15 healthy volunteers. Nine image features were extracted from each RTE image and a multiple regression analysis was then performed to derive the regression equation. This equation calculates Liver Fibrosis Index (LF Index), which in turn predicts F stage of the liver. LF Index not only correlates highly with the F stage (r = 0.68) of the liver fibrosis, but also it shows significant differences in LF Index values (p < 0.001) between each stage of the fibrosis. Thus, we can conclude that RTE is a promising method to evaluate the liver fibrosis noninvasively.
- LF Index
- Liver fibrosis index
- Real-time tissue elastography
ASJC Scopus subject areas