TY - JOUR
T1 - Non-invasive evaluation method of the liver fibrosis using Real-time tissue elastograpy - Usefulness of judgment liver fibrosis stage by Liver fibrosis index (LF index)
AU - Fujimoto, Kenji
AU - Kato, Michio
AU - Tonomura, Akiko
AU - Yada, Norihisa
AU - Tatsumi, Chie
AU - Oshita, Masahide
AU - Wada, Shigeo
AU - Ueshima, Kazuomi
AU - Ishida, Tetsushi
AU - Furuta, Tomoko
AU - Yamasaki, Masaru
AU - Tsujimoto, Masahiko
AU - Motoki, Mitsuru
AU - Mitake, Tsuyoshi
AU - Kim, Shigehiro
AU - Yamamoto, Keiji
AU - Shiina, Tsuyoshi
AU - Kudo, Masatoshi
AU - Hayashi, Norio
PY - 2010
Y1 - 2010
N2 - To evaluate the effectiveness of Real-time Tissue Elastography (RTE) in staging of liver fibrosis noninvasively, we performed RTE on 310 patients with chronic hepatitis C (and/or liver cirrhosis) and 15 healthy volunteers. Nine image features were extracted from each RTE image and a multiple regression analysis was then performed to derive the regression equation. This equation calculates Liver Fibrosis Index (LF Index), which in turn predicts F stage of the liver. LF Index not only correlates highly with the F stage (r = 0.68) of the liver fibrosis, but also it shows significant differences in LF Index values (p < 0.001) between each stage of the fibrosis. Thus, we can conclude that RTE is a promising method to evaluate the liver fibrosis noninvasively.
AB - To evaluate the effectiveness of Real-time Tissue Elastography (RTE) in staging of liver fibrosis noninvasively, we performed RTE on 310 patients with chronic hepatitis C (and/or liver cirrhosis) and 15 healthy volunteers. Nine image features were extracted from each RTE image and a multiple regression analysis was then performed to derive the regression equation. This equation calculates Liver Fibrosis Index (LF Index), which in turn predicts F stage of the liver. LF Index not only correlates highly with the F stage (r = 0.68) of the liver fibrosis, but also it shows significant differences in LF Index values (p < 0.001) between each stage of the fibrosis. Thus, we can conclude that RTE is a promising method to evaluate the liver fibrosis noninvasively.
KW - LF Index
KW - Liver fibrosis index
KW - Real-time tissue elastography
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U2 - 10.2957/kanzo.51.539
DO - 10.2957/kanzo.51.539
M3 - Article
AN - SCOPUS:78049397472
SN - 0451-4203
VL - 51
SP - 539
EP - 541
JO - Acta Hepatologica Japonica
JF - Acta Hepatologica Japonica
IS - 9
ER -