Abstract
Objective: The aim of this study was to investigate liver fibrosis using non-invasive Real-time Tissue Elastography® (RTE) and transient elastography (FibroScan®) methods. Methods: RTE, FibroScan and percutaneous liver biopsy were all performed on patients with chronic liver disease, particularly hepatitis C, to investigate liver fibrosis. Results: FibroScan and RTE were compared for fibrous liver staging (F stage), which was pathologically classified using liver biopsy. In FibroScan, significant differences were observed between F1/F3 and F2/F4, but no such differences were observed between F1/F2, F2/F3 and F3/F4. In RTE, significant differences were observed between F1/F2, F2/F3 and F2/F4. But for F3/F4, no significant differences were observed. Conclusion: FibroScan and RTE correlated well with F staging of the liver. In particular RTE was more successful than FibroScan in diagnosing the degree of liver fibrosis.
Original language | English |
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Pages (from-to) | 76-81 |
Number of pages | 6 |
Journal | Intervirology |
Volume | 53 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2010 Jan |
Externally published | Yes |
Keywords
- Biopsy, liver
- FibroScan
- Fibrosis, liver
- Real-time tissue elastography
ASJC Scopus subject areas
- Virology
- Infectious Diseases