Noninvasive imaging of prefrontal activation during attention-demanding tasks performed while walking using a wearable optical topography system

Hirokazu Atsumori, Masashi Kiguchi, Takusige Katura, Tsukasa Funane, Akiko Obata, Hiroki Satou, Takaaki Manaka, Mitsumasa Iwamoto, Atsushi Maki, Hideaki Koizumi, Kisou Kubota

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Optical topography (OT) based on near-infrared spectroscopy is a noninvasive technique for mapping the relative concentration changes in oxygenated and deoxygenated hemoglobin (oxy- and deoxy-Hb, respectively) in the human cerebral cortex. In our previous study, we developed a small and light wearable optical topography (WOT) system that covers the entire forehead for monitoring prefrontal activation. In the present study, we examine whether the WOT system is applicable to OT measurement while walking, which has been difficult with conventional OT systems. We conduct OT measurements while subjects perform an attention-demanding (AD) task of balancing a ping-pong ball on a small card while walking. The measured time course and power spectra of the relative concentration changes in oxy- and deoxy-Hb show that the step-related changes in the oxy- and deoxy-Hb signals are negligible compared to the taskrelated changes. Statistical assessment of the task-related changes in the oxy-Hb signals show that the dorsolateral prefrontal cortex and rostral prefrontal area are significantly activated during the AD task. These results suggest that our functional imaging technique with the WOT system is applicable to OT measurement while walking, and will be a powerful tool for evaluating brain activation in a natural environment.

Original languageEnglish
Article number046002
JournalJournal of Biomedical Optics
Volume15
Issue number4
DOIs
Publication statusPublished - 2010 Jul 1
Externally publishedYes

Fingerprint

walking
Topography
topography
Chemical activation
activation
Imaging techniques
forehead
cerebral cortex
Near infrared spectroscopy
cortexes
Hemoglobin
hemoglobin
cards
Power spectrum
imaging techniques
brain
power spectra
balls
Brain
Hemoglobins

Keywords

  • Attention
  • Walking
  • Wearable optical topography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

Cite this

Noninvasive imaging of prefrontal activation during attention-demanding tasks performed while walking using a wearable optical topography system. / Atsumori, Hirokazu; Kiguchi, Masashi; Katura, Takusige; Funane, Tsukasa; Obata, Akiko; Satou, Hiroki; Manaka, Takaaki; Iwamoto, Mitsumasa; Maki, Atsushi; Koizumi, Hideaki; Kubota, Kisou.

In: Journal of Biomedical Optics, Vol. 15, No. 4, 046002, 01.07.2010.

Research output: Contribution to journalArticle

Atsumori, H, Kiguchi, M, Katura, T, Funane, T, Obata, A, Satou, H, Manaka, T, Iwamoto, M, Maki, A, Koizumi, H & Kubota, K 2010, 'Noninvasive imaging of prefrontal activation during attention-demanding tasks performed while walking using a wearable optical topography system', Journal of Biomedical Optics, vol. 15, no. 4, 046002. https://doi.org/10.1117/1.3462996
Atsumori, Hirokazu ; Kiguchi, Masashi ; Katura, Takusige ; Funane, Tsukasa ; Obata, Akiko ; Satou, Hiroki ; Manaka, Takaaki ; Iwamoto, Mitsumasa ; Maki, Atsushi ; Koizumi, Hideaki ; Kubota, Kisou. / Noninvasive imaging of prefrontal activation during attention-demanding tasks performed while walking using a wearable optical topography system. In: Journal of Biomedical Optics. 2010 ; Vol. 15, No. 4.
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