On-chip cell manipulation by magnetically modified soft microactuators

Yoko Yamanishi, Shinya Sakuma, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Citations (Scopus)

Abstract

We have developed magnetically modified polymeric soft microactuators in microchip as replacement of conventional manual cell manipulations such as pipetting and centrifugation. In the past papers [1] we have reported novel magnetically driven polymeric microtools for non-intrusive and no contamination experiments on a chip. The main features of them were 1. fabrication of any shape, 2. soft (harmless to cellls) 3. no stiction and 4. mass production at low cost enabling disposability. For the current research, we have demonstrated manipulation of oocyte with produced novel soft microactuators. These magnetic microtools provide a number of functions such as microvalve and microrotor. The potential impact of this technology includes sample preparations, selection and separation, loading and immobilization, genetic operation, tracking, mixing and reaction techniques into portable microfluidic labs-on-a-chip, culture systems.

Original languageEnglish
Title of host publication2008 IEEE International Conference on Robotics and Automation, ICRA 2008
Pages899-904
Number of pages6
DOIs
Publication statusPublished - 2008 Sep 18
Event2008 IEEE International Conference on Robotics and Automation, ICRA 2008 - Pasadena, CA, United States
Duration: 2008 May 192008 May 23

Publication series

NameProceedings - IEEE International Conference on Robotics and Automation
ISSN (Print)1050-4729

Other

Other2008 IEEE International Conference on Robotics and Automation, ICRA 2008
CountryUnited States
CityPasadena, CA
Period08/5/1908/5/23

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ASJC Scopus subject areas

  • Software
  • Control and Systems Engineering
  • Artificial Intelligence
  • Electrical and Electronic Engineering

Cite this

Yamanishi, Y., Sakuma, S., & Arai, F. (2008). On-chip cell manipulation by magnetically modified soft microactuators. In 2008 IEEE International Conference on Robotics and Automation, ICRA 2008 (pp. 899-904). [4543319] (Proceedings - IEEE International Conference on Robotics and Automation). https://doi.org/10.1109/ROBOT.2008.4543319