On-chip magnetically driven micro-robot for enucleation of oocyte

Naoki Inomata, Takehito Mizunuma, Yoko Yamanishi, Shogo Kudo, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

We developed a magnetically driven microtool(MMT) used in a microfluidic chip for enucleation of oocyte. To achieve technological innovation, weight of the tool is about 1/300,000 compared with that of the conventional mechanical micromanipulator and was installed in a chip. We succeeded in precise positioning of the tool (5 μm) with low disturbances. The tool is actuated noncontact by the magnetic force, therefore, the microfluidic chip part is fully disposable with low cost. Of special notes are following. (1) Novel vibrating type of MMT is proposed to reduce the dead band of the magnetic actuation. (2) Omni-directional actuation of the tool was achieved by controlling magnetic field focused on a chip. (3) Backlash of the tool was reduced by supporting it by the flexible hinge with isotropic spring constant. (4) A polymer-metal hybrid structure which has properties of both elasticity and rigidity was employed for the tool. (5) Based on the novel and original design, we integrated a Robot-on-a-Chip (Robochip) and demonstrated on-chip enucleation of oocyte.

Original languageEnglish
Title of host publication20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
Pages493-498
Number of pages6
DOIs
Publication statusPublished - 2009
Event20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science - Nagoya, Japan
Duration: 2009 Nov 82009 Nov 11

Publication series

Name20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science

Conference

Conference20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
CountryJapan
CityNagoya
Period09/11/809/11/11

ASJC Scopus subject areas

  • Computer Science(all)
  • Control and Systems Engineering
  • Electrical and Electronic Engineering

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    Inomata, N., Mizunuma, T., Yamanishi, Y., Kudo, S., & Arai, F. (2009). On-chip magnetically driven micro-robot for enucleation of oocyte. In 20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science (pp. 493-498). [5351824] (20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science). https://doi.org/10.1109/MHS.2009.5351824