On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure

Tomohiro Kawahara, Masakuni Sugita, Masaya Hagiwara, Yoko Yamanishi, Fumihito Arai, Hiroyuki Kawano, Ikuko Shihira-Ishikawa, Atsushi Miyawaki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

In this paper, we introduce an untethered type of magnetically driven microtool (MMT) with a force sensing function to investigate the stimulus characteristics of aquatic microorganisms in a microfluidic chip. The microchip is composed of the proposed MMTs, which have a Si-Ni hybrid structure, a transparent cover made of polydimethylsiloxane (PDMS), a glass substrate, and a microspacer to prevent both friction during the force measurement and damage to the micropattern of the MMT. The fabrication and drive performance of the MMT, which is actuated by permanent magnets from the outside of the microchip, verified in basic experiments. Finally, we succeeded in on-chip manipulation and sensing of microorganisms using this MMT, which we found to be easy to use.

Original languageEnglish
Title of host publicationProceedings - IEEE International Conference on Robotics and Automation
Pages4112-4117
Number of pages6
DOIs
Publication statusPublished - 2012
Externally publishedYes

Fingerprint

Microorganisms
Force measurement
Polydimethylsiloxane
Microfluidics
Permanent magnets
Friction
Fabrication
Glass
Substrates
Experiments

ASJC Scopus subject areas

  • Software
  • Artificial Intelligence
  • Control and Systems Engineering
  • Electrical and Electronic Engineering

Cite this

Kawahara, T., Sugita, M., Hagiwara, M., Yamanishi, Y., Arai, F., Kawano, H., ... Miyawaki, A. (2012). On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. In Proceedings - IEEE International Conference on Robotics and Automation (pp. 4112-4117). [6224966] https://doi.org/10.1109/ICRA.2012.6224966

On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. / Kawahara, Tomohiro; Sugita, Masakuni; Hagiwara, Masaya; Yamanishi, Yoko; Arai, Fumihito; Kawano, Hiroyuki; Shihira-Ishikawa, Ikuko; Miyawaki, Atsushi.

Proceedings - IEEE International Conference on Robotics and Automation. 2012. p. 4112-4117 6224966.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kawahara, T, Sugita, M, Hagiwara, M, Yamanishi, Y, Arai, F, Kawano, H, Shihira-Ishikawa, I & Miyawaki, A 2012, On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. in Proceedings - IEEE International Conference on Robotics and Automation., 6224966, pp. 4112-4117. https://doi.org/10.1109/ICRA.2012.6224966
Kawahara T, Sugita M, Hagiwara M, Yamanishi Y, Arai F, Kawano H et al. On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. In Proceedings - IEEE International Conference on Robotics and Automation. 2012. p. 4112-4117. 6224966 https://doi.org/10.1109/ICRA.2012.6224966
Kawahara, Tomohiro ; Sugita, Masakuni ; Hagiwara, Masaya ; Yamanishi, Yoko ; Arai, Fumihito ; Kawano, Hiroyuki ; Shihira-Ishikawa, Ikuko ; Miyawaki, Atsushi. / On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. Proceedings - IEEE International Conference on Robotics and Automation. 2012. pp. 4112-4117
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