On-chip particle sorting into multiple channels by magnetically driven microtools

Masaya Hagiwara, Miyako Niimi, Tomohiro Kawahara, Yoko Yamanishi, Hayao Nakanishi, Fumihito Arai

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

This paper presents a new type of sorting system by magnetic microtools (MMT) separating particles into multiple channels. Two nickel-based MMTs are activated by commercially available permanent magnets below the biochip to lead particles to certain channels via fluid force. The horizontally assembled permanent magnet drive we developed shows that the MMT positioning accuracy had been improved 5 times in 2 degrees of freedom. The channel and the MMT shape are determined based on FEM analysis to ensure that particles flow smoothly. We have successfully achieved to sort 100 μm diameter microbeads into 7 branched channels. The noncontact drive and disposable chip provide a less invasive environment for the cell with low cost.

Original languageEnglish
Pages (from-to)370-377
Number of pages8
JournalJournal of Robotics and Mechatronics
Volume23
Issue number3
DOIs
Publication statusPublished - 2011 Jun

Keywords

  • Lab on a chip
  • Magnetically driven microtool
  • Microactuator
  • Sorter

ASJC Scopus subject areas

  • Computer Science(all)
  • Electrical and Electronic Engineering

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  • Cite this

    Hagiwara, M., Niimi, M., Kawahara, T., Yamanishi, Y., Nakanishi, H., & Arai, F. (2011). On-chip particle sorting into multiple channels by magnetically driven microtools. Journal of Robotics and Mechatronics, 23(3), 370-377. https://doi.org/10.20965/jrm.2011.p0370