Optical topography: Practical problems and new applications

Hideaki Koizumi, Tsuyoshi Yamamoto, Atsushi Maki, Yuichi Yamashita, Hiroki Sato, Hideo Kawaguchi, Noriyoshi Ichikawa

Research output: Contribution to journalArticlepeer-review

141 Citations (Scopus)


We will briefly review the present status of optical topography and then discuss the method of improving practicality, i.e., the signal-to-noise (S/N) ratio and the spatial resolution in observations of higher-order brain functions. The optimum wavelength pair improved the (S/N)ratio sixfold for deoxyhemoglobin, and new configurations of light irradiation and detection positions doubled the spatial resolution. We also report on developing application fields of optical topography. This modality will bridge the gap between natural sciences, neuroscience, and pedagogy, and show actual real-time brain activity.

Original languageEnglish
Pages (from-to)3054-3062
Number of pages9
JournalApplied Optics
Issue number16
Publication statusPublished - 2003 Jun 1
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering


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