Oxygen consumption by vascular wall in skeletal muscle arterioles under physiological conditions

Masahiro Shibata, T. Yamakoshi, K. Yamakoshi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To examine the large drop of partial oxygen pressure (P02) in arterioles, the 02 consumption rates of arteriolar walls were determined under physiological conditions. A phosphorescence quenching technique was used to quantify the intra and perivascular P02 values in rat cremaster arterioles. Using the measured P02 values, and a theoretical model, the 02 consumption rates of the arteriolar walls were then estimated. We found that the 02 consumption rate of arterioles was 100 times greater than that seen in in vitro experiments, and the 02 consumption rate under normal conditions was significantly higher than that during vasodilation. Furthermore, the 02 consumption rate was the highest in the upstream arterioles. These findings suggest that the high 02 consumption rates of arteriolar walls depend on the workload of the smooth muscle.

Original languageEnglish
Title of host publication8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008
DOIs
Publication statusPublished - 2008
Event8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008 - Athens
Duration: 2008 Oct 82008 Oct 10

Other

Other8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008
CityAthens
Period08/10/808/10/10

Fingerprint

Phosphorescence
Muscle
Rats
Quenching
Oxygen
Experiments
Vasodilation

Keywords

  • Arterioles
  • Oxygen consumption
  • Oxygen transport
  • Skeletal muscle
  • Vascular wall

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

Cite this

Shibata, M., Yamakoshi, T., & Yamakoshi, K. (2008). Oxygen consumption by vascular wall in skeletal muscle arterioles under physiological conditions. In 8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008 [4696828] https://doi.org/10.1109/BIBE.2008.4696828

Oxygen consumption by vascular wall in skeletal muscle arterioles under physiological conditions. / Shibata, Masahiro; Yamakoshi, T.; Yamakoshi, K.

8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008. 2008. 4696828.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shibata, M, Yamakoshi, T & Yamakoshi, K 2008, Oxygen consumption by vascular wall in skeletal muscle arterioles under physiological conditions. in 8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008., 4696828, 8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008, Athens, 08/10/8. https://doi.org/10.1109/BIBE.2008.4696828
Shibata M, Yamakoshi T, Yamakoshi K. Oxygen consumption by vascular wall in skeletal muscle arterioles under physiological conditions. In 8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008. 2008. 4696828 https://doi.org/10.1109/BIBE.2008.4696828
Shibata, Masahiro ; Yamakoshi, T. ; Yamakoshi, K. / Oxygen consumption by vascular wall in skeletal muscle arterioles under physiological conditions. 8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008. 2008.
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