Oxygen consumption by vascular wall in skeletal muscle arterioles under physiological conditions

M. Shibata, T. Yamakoshi, K. Yamakoshi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To examine the large drop of partial oxygen pressure (P02) in arterioles, the 02 consumption rates of arteriolar walls were determined under physiological conditions. A phosphorescence quenching technique was used to quantify the intra and perivascular P02 values in rat cremaster arterioles. Using the measured P02 values, and a theoretical model, the 02 consumption rates of the arteriolar walls were then estimated. We found that the 02 consumption rate of arterioles was 100 times greater than that seen in in vitro experiments, and the 02 consumption rate under normal conditions was significantly higher than that during vasodilation. Furthermore, the 02 consumption rate was the highest in the upstream arterioles. These findings suggest that the high 02 consumption rates of arteriolar walls depend on the workload of the smooth muscle.

Original languageEnglish
Title of host publication8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008
DOIs
Publication statusPublished - 2008 Dec 1
Event8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008 - Athens, Greece
Duration: 2008 Oct 82008 Oct 10

Publication series

Name8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008

Conference

Conference8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008
CountryGreece
CityAthens
Period08/10/808/10/10

Keywords

  • Arterioles
  • Oxygen consumption
  • Oxygen transport
  • Skeletal muscle
  • Vascular wall

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

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  • Cite this

    Shibata, M., Yamakoshi, T., & Yamakoshi, K. (2008). Oxygen consumption by vascular wall in skeletal muscle arterioles under physiological conditions. In 8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008 [4696828] (8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008). https://doi.org/10.1109/BIBE.2008.4696828