Permanent magnets circuit for collagen orientation

Tadashi Shinohara, Tomoyuki Saito, Daisuke Saito, Makoto Kotani, Masaaki Aoki

Research output: Contribution to journalArticle

Abstract

To synthesize artificial bones, the collagen orientation is one of the key issues. It is reported that high magnetic field could be generated by superconducting magnets, are effective in controlling collagen orientation. In this paper, magnetic circuit using permanent magnets for collagen orientation is studied. As the results, a compact magnetic circuit with magnetic field strength around 3 T has been developed. By using the magnetic circuit, collagen was highly oriented, and orientation order was 0.9. Mouse osteoblast cells were seeded on the orientated collagen solution and cultured. The collagen-gel shrinkages by cells were observed. The shrinkage rates of oriented collagen are higher than that of not oriented one.

Original languageEnglish
Pages (from-to)4333-4336
Number of pages4
JournalPhysica Status Solidi (C) Current Topics in Solid State Physics
Volume4
Issue number12
DOIs
Publication statusPublished - 2007

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collagens
permanent magnets
magnetic circuits
shrinkage
osteoblasts
superconducting magnets
cells
magnetic fields
bones
mice
field strength
gels

ASJC Scopus subject areas

  • Condensed Matter Physics

Cite this

Permanent magnets circuit for collagen orientation. / Shinohara, Tadashi; Saito, Tomoyuki; Saito, Daisuke; Kotani, Makoto; Aoki, Masaaki.

In: Physica Status Solidi (C) Current Topics in Solid State Physics, Vol. 4, No. 12, 2007, p. 4333-4336.

Research output: Contribution to journalArticle

Shinohara, Tadashi ; Saito, Tomoyuki ; Saito, Daisuke ; Kotani, Makoto ; Aoki, Masaaki. / Permanent magnets circuit for collagen orientation. In: Physica Status Solidi (C) Current Topics in Solid State Physics. 2007 ; Vol. 4, No. 12. pp. 4333-4336.
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