Permanent magnets circuit for collagen orientation

Tadashi Shinohara, Tomoyuki Saito, Daisuke Saito, Makoto Kotani, Masaaki Aoki

Research output: Contribution to journalConference articlepeer-review


To synthesize artificial bones, the collagen orientation is one of the key issues. It is reported that high magnetic field could be generated by superconducting magnets, are effective in controlling collagen orientation. In this paper, magnetic circuit using permanent magnets for collagen orientation is studied. As the results, a compact magnetic circuit with magnetic field strength around 3 T has been developed. By using the magnetic circuit, collagen was highly oriented, and orientation order was 0.9. Mouse osteoblast cells were seeded on the orientated collagen solution and cultured. The collagen-gel shrinkages by cells were observed. The shrinkage rates of oriented collagen are higher than that of not oriented one.

Original languageEnglish
Pages (from-to)4333-4336
Number of pages4
JournalPhysica Status Solidi (C) Current Topics in Solid State Physics
Issue number12
Publication statusPublished - 2007
Externally publishedYes
EventInternational Symposium on Advanced Magnetic Materials and Appilications, (ISAMMA 2007) - Jeju, Korea, Republic of
Duration: 2007 May 282007 Jun 1

ASJC Scopus subject areas

  • Condensed Matter Physics


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