PO2-dependent regulation of microvascular blood flow in skeletal muscle

M. Shibata, A. Kawarada, J. Ando, A. Kamiya, T. Togawa

Research output: Contribution to journalConference articlepeer-review


The pO2-dependent regulation of microvascular blood flow was evaluated in rabbit skeletal muscle in vivo. The tenuissimus muscle was prepared to observe the microcirculation. The mean red blood cell velocity and perfused capillary density at various tissue pO2 levels were measured using an intravital video-microscope. Both velocity and density were significantly decreased as tissue pO2 was elevated, but the relationship between capillary flow and tissue pO2 was not a linear correlation. In addition, the critical pO2 value effected on microvascular blood flow regulation may exist in the tissue pO2 ranging from 30 to 50 mmHg, which might be detected in the region of arteriolar walls.

Original languageEnglish
Pages (from-to)81-82
Number of pages2
JournalAnnual Reports of the Research Reactor Institute, Kyoto University
Publication statusPublished - 2001
Externally publishedYes
Event23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey
Duration: 2001 Oct 252001 Oct 28


  • Capillary blood flow
  • Oxygen tension
  • Skeletal muscle

ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Mechanical Engineering


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