PO2-dependent regulation of microvascular blood flow in skeletal muscle

M. Shibata; A. Kawarada; J. Ando; A. Kamiya; T. Togawa

PO₂-dependent regulation of microvascular blood flow in skeletal muscle

M. Shibata, A. Kawarada, J. Ando, A. Kamiya, T. Togawa

Research output: Contribution to journal › Conference article › peer-review

Abstract

The pO₂-dependent regulation of microvascular blood flow was evaluated in rabbit skeletal muscle in vivo. The tenuissimus muscle was prepared to observe the microcirculation. The mean red blood cell velocity and perfused capillary density at various tissue pO₂ levels were measured using an intravital video-microscope. Both velocity and density were significantly decreased as tissue pO₂ was elevated, but the relationship between capillary flow and tissue pO₂ was not a linear correlation. In addition, the critical pO₂ value effected on microvascular blood flow regulation may exist in the tissue pO₂ ranging from 30 to 50 mmHg, which might be detected in the region of arteriolar walls.

Original language	English
Pages (from-to)	81-82
Number of pages	2
Journal	Annual Reports of the Research Reactor Institute, Kyoto University
Volume	1
Publication status	Published - 2001 Dec 1
Externally published	Yes
Event	23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey Duration: 2001 Oct 25 → 2001 Oct 28

Keywords

Capillary blood flow
Oxygen tension
Skeletal muscle

ASJC Scopus subject areas

Energy Engineering and Power Technology
Mechanical Engineering

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title = "PO2-dependent regulation of microvascular blood flow in skeletal muscle",

abstract = "The pO2-dependent regulation of microvascular blood flow was evaluated in rabbit skeletal muscle in vivo. The tenuissimus muscle was prepared to observe the microcirculation. The mean red blood cell velocity and perfused capillary density at various tissue pO2 levels were measured using an intravital video-microscope. Both velocity and density were significantly decreased as tissue pO2 was elevated, but the relationship between capillary flow and tissue pO2 was not a linear correlation. In addition, the critical pO2 value effected on microvascular blood flow regulation may exist in the tissue pO2 ranging from 30 to 50 mmHg, which might be detected in the region of arteriolar walls.",

keywords = "Capillary blood flow, Oxygen tension, Skeletal muscle",

author = "M. Shibata and A. Kawarada and J. Ando and A. Kamiya and T. Togawa",

year = "2001",

month = dec,

day = "1",

language = "English",

volume = "1",

pages = "81--82",

journal = "Annual Reports of the Research Reactor Institute, Kyoto University",

issn = "0454-9244",

note = "23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society ; Conference date: 25-10-2001 Through 28-10-2001",

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TY - JOUR

T1 - PO2-dependent regulation of microvascular blood flow in skeletal muscle

AU - Shibata, M.

AU - Kawarada, A.

AU - Ando, J.

AU - Kamiya, A.

AU - Togawa, T.

PY - 2001/12/1

Y1 - 2001/12/1

N2 - The pO2-dependent regulation of microvascular blood flow was evaluated in rabbit skeletal muscle in vivo. The tenuissimus muscle was prepared to observe the microcirculation. The mean red blood cell velocity and perfused capillary density at various tissue pO2 levels were measured using an intravital video-microscope. Both velocity and density were significantly decreased as tissue pO2 was elevated, but the relationship between capillary flow and tissue pO2 was not a linear correlation. In addition, the critical pO2 value effected on microvascular blood flow regulation may exist in the tissue pO2 ranging from 30 to 50 mmHg, which might be detected in the region of arteriolar walls.

AB - The pO2-dependent regulation of microvascular blood flow was evaluated in rabbit skeletal muscle in vivo. The tenuissimus muscle was prepared to observe the microcirculation. The mean red blood cell velocity and perfused capillary density at various tissue pO2 levels were measured using an intravital video-microscope. Both velocity and density were significantly decreased as tissue pO2 was elevated, but the relationship between capillary flow and tissue pO2 was not a linear correlation. In addition, the critical pO2 value effected on microvascular blood flow regulation may exist in the tissue pO2 ranging from 30 to 50 mmHg, which might be detected in the region of arteriolar walls.

KW - Capillary blood flow

KW - Oxygen tension

KW - Skeletal muscle

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M3 - Conference article

AN - SCOPUS:0035782274

VL - 1

SP - 81

EP - 82

JO - Annual Reports of the Research Reactor Institute, Kyoto University

JF - Annual Reports of the Research Reactor Institute, Kyoto University

SN - 0454-9244

T2 - 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Y2 - 25 October 2001 through 28 October 2001

ER -