Preparation of highly photosensitizing liposomes with fullerene-doped lipid bilayer using dispersion-controllable molecular exchange reactions

Atsushi Ikeda, Tatsuya Sue, Motofusa Akiyama, Katsuyoshi Fujioka, Tamami Shigematsu, Yuki Doi, Jun Ichi Kikuchi, Toshifumi Konishi, Riichiro Nakajima

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

(Figure Presented) Fullerene-containing liposomes with high photosensitization ability were prepared. Disaggregated fullerenes were efficiently injected into the bilayer of liposomes by a phototriggered molecular exchange reaction. These liposomes showed far higher photoreactivity than liposomes thermally produced by heating and microwave irradiation. This result indicates that control of self-aggregation of fullerene leads to a high quantum yield for the photoreaction because of the suppression of self-quenching of photoexcited fullerenes.

Original languageEnglish
Pages (from-to)4077-4080
Number of pages4
JournalOrganic Letters
Volume10
Issue number18
DOIs
Publication statusPublished - 2008 Dec 1

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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