Probing into adsorption behavior of human plasma fibrinogen on self-assembled monolayers with different chemical properties by scanning probe microscopy

Takahiro Ishizaki, Nagahiro Saito, Yuki Sato, Osamu Takai

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The adsorption behaviors of fibrinogen on the self-assembled monolayers (SAMs) with different chemical properties were investigated using an atomic force microscopy (AFM). AFM images indicated that the adsorption amounts of fibrinogen molecules increased with an increase of the surface hydrophobicity. High-resolution AFM imaging revealed that the fibrinogen conformations adsorbed on the SAM surface changed with dependent on the surface chemistry. The adsorption models of fibrinogen molecules adsorbed on SAM surfaces with different chemical properties were proposed based on the high-resolution AFM images.

Original languageEnglish
Pages (from-to)3861-3865
Number of pages5
JournalSurface Science
Volume601
Issue number18
DOIs
Publication statusPublished - 2007 Sep 15
Externally publishedYes

Fingerprint

Plasma (human)
fibrinogen
Scanning probe microscopy
Self assembled monolayers
chemical properties
Fibrinogen
Chemical properties
Atomic force microscopy
atomic force microscopy
microscopy
Adsorption
adsorption
scanning
probes
Molecules
high resolution
Hydrophobicity
hydrophobicity
Surface chemistry
Conformations

Keywords

  • AFM
  • Fibrinogen
  • SAM

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Condensed Matter Physics
  • Surfaces and Interfaces

Cite this

Probing into adsorption behavior of human plasma fibrinogen on self-assembled monolayers with different chemical properties by scanning probe microscopy. / Ishizaki, Takahiro; Saito, Nagahiro; Sato, Yuki; Takai, Osamu.

In: Surface Science, Vol. 601, No. 18, 15.09.2007, p. 3861-3865.

Research output: Contribution to journalArticle

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