Propionibacterium acidipropionici TISTR442 produced the highest amount of 5-aminolevulinic acid (ALA) when cultivated in medium supplemented with glycine at 18. g/l ALA production correlated with ALA synthase activity, whereas ALA dehydratase activity was maintained at a low level. ALA yield reached 405. mg/l after prolonged cultivation for 1 month.
- 5-Aminolevulinic acid
- ALA dehydratase
- ALA synthase
- Propionibacterium acidipropionici
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology