Production of 5-aminolevulinic acid by Propionibacterium acidipropionici TISTR442

Pornpimon Kiatpapan, Manthana Phonghatsabun, Mitsuo Yamashita, Yoshikatsu Murooka, Watanalai Panbangred

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Propionibacterium acidipropionici TISTR442 produced the highest amount of 5-aminolevulinic acid (ALA) when cultivated in medium supplemented with glycine at 18. g/l ALA production correlated with ALA synthase activity, whereas ALA dehydratase activity was maintained at a low level. ALA yield reached 405. mg/l after prolonged cultivation for 1 month.

Original languageEnglish
Pages (from-to)425-428
Number of pages4
JournalJournal of Bioscience and Bioengineering
Issue number4
Publication statusPublished - 2011 Apr
Externally publishedYes


  • 5-Aminolevulinic acid
  • ALA dehydratase
  • ALA synthase
  • Glycine
  • Propionibacterium acidipropionici

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


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