Proposal for artificial bone formation using powder-layered manufacturing

Porous characteristics of forming bone

Kenji Yamazawa, Masahiro Anzai, Hideo Yokota, Ryutaro Himeno, Hiroshi Suzuki, Hiroyuki Narahara

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In this study, we proposed a powder-layered manufacturing process, which is one technique for rapid prototyping, to produce the desired bone shape for a transplantation from a biomaterial powder. In the experiment, we used conventional inkjet-type equipment and orthopedic filling-paste powder (BIOPEX), of which the main component was alpha-tribasic calcium phosphate, as the forming material. To solidify the powder, we used a sodium chondroitin sulfate + dibasic sodium succinate anhydride aqueous solution-the solvent for mixing powder in clinics-as the binder liquid. In the previous report, we formed a geometric model and living bone to examine the formability of artificial bones, and showed that the formation of artificial bones is possible using this technique. In this paper, we investigated porous characteristics, an important condition for artificial bones. In experiments, we formed cylindrical samples (dimensions:7 mm in diameter, 20 mm in length) by powder-layered manufacturing (PM) and using filling-paste (FP) which is also used in clinical applications. Then we compared the porous characteristics of these samples using mercury porosimetry. The results showed that in the case of PM, porosity was 60%, about three times FP. In addition, we dipped PM samples in water and binder liquid for improving compressive strength by hydration reaction. The compressive strength of two kinds of dipped samples reached about 3 MPa when heated at 90 °C for five hours. Porosity was about 56% when dipped in water, and about 50% when dipped in binder liquid.

Original languageEnglish
Pages (from-to)142-147
Number of pages6
JournalTransactions of Japanese Society for Medical and Biological Engineering
Volume47
Issue number2
Publication statusPublished - 2009
Externally publishedYes

Fingerprint

Layered manufacturing
Bone
Powders
Binders
Compressive strength
Liquids
Porosity
Sodium sulfate
Orthopedics
Calcium phosphate
Rapid prototyping
Formability
Biomaterials
Hydration
Water
Experiments
Sodium

Keywords

  • Artificial bone
  • Inkjet
  • Layered manufacturing
  • Porosity
  • Rapid prototyping

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Proposal for artificial bone formation using powder-layered manufacturing : Porous characteristics of forming bone. / Yamazawa, Kenji; Anzai, Masahiro; Yokota, Hideo; Himeno, Ryutaro; Suzuki, Hiroshi; Narahara, Hiroyuki.

In: Transactions of Japanese Society for Medical and Biological Engineering, Vol. 47, No. 2, 2009, p. 142-147.

Research output: Contribution to journalArticle

@article{ac9d3734834d4e43a14cb91ecd0cab8a,
title = "Proposal for artificial bone formation using powder-layered manufacturing: Porous characteristics of forming bone",
abstract = "In this study, we proposed a powder-layered manufacturing process, which is one technique for rapid prototyping, to produce the desired bone shape for a transplantation from a biomaterial powder. In the experiment, we used conventional inkjet-type equipment and orthopedic filling-paste powder (BIOPEX), of which the main component was alpha-tribasic calcium phosphate, as the forming material. To solidify the powder, we used a sodium chondroitin sulfate + dibasic sodium succinate anhydride aqueous solution-the solvent for mixing powder in clinics-as the binder liquid. In the previous report, we formed a geometric model and living bone to examine the formability of artificial bones, and showed that the formation of artificial bones is possible using this technique. In this paper, we investigated porous characteristics, an important condition for artificial bones. In experiments, we formed cylindrical samples (dimensions:7 mm in diameter, 20 mm in length) by powder-layered manufacturing (PM) and using filling-paste (FP) which is also used in clinical applications. Then we compared the porous characteristics of these samples using mercury porosimetry. The results showed that in the case of PM, porosity was 60{\%}, about three times FP. In addition, we dipped PM samples in water and binder liquid for improving compressive strength by hydration reaction. The compressive strength of two kinds of dipped samples reached about 3 MPa when heated at 90 °C for five hours. Porosity was about 56{\%} when dipped in water, and about 50{\%} when dipped in binder liquid.",
keywords = "Artificial bone, Inkjet, Layered manufacturing, Porosity, Rapid prototyping",
author = "Kenji Yamazawa and Masahiro Anzai and Hideo Yokota and Ryutaro Himeno and Hiroshi Suzuki and Hiroyuki Narahara",
year = "2009",
language = "English",
volume = "47",
pages = "142--147",
journal = "BME = Bio medical engineering / henshu, Nihon ME Gakkai",
issn = "1347-443X",
publisher = "Nihon M E Gakkai",
number = "2",

}

TY - JOUR

T1 - Proposal for artificial bone formation using powder-layered manufacturing

T2 - Porous characteristics of forming bone

AU - Yamazawa, Kenji

AU - Anzai, Masahiro

AU - Yokota, Hideo

AU - Himeno, Ryutaro

AU - Suzuki, Hiroshi

AU - Narahara, Hiroyuki

PY - 2009

Y1 - 2009

N2 - In this study, we proposed a powder-layered manufacturing process, which is one technique for rapid prototyping, to produce the desired bone shape for a transplantation from a biomaterial powder. In the experiment, we used conventional inkjet-type equipment and orthopedic filling-paste powder (BIOPEX), of which the main component was alpha-tribasic calcium phosphate, as the forming material. To solidify the powder, we used a sodium chondroitin sulfate + dibasic sodium succinate anhydride aqueous solution-the solvent for mixing powder in clinics-as the binder liquid. In the previous report, we formed a geometric model and living bone to examine the formability of artificial bones, and showed that the formation of artificial bones is possible using this technique. In this paper, we investigated porous characteristics, an important condition for artificial bones. In experiments, we formed cylindrical samples (dimensions:7 mm in diameter, 20 mm in length) by powder-layered manufacturing (PM) and using filling-paste (FP) which is also used in clinical applications. Then we compared the porous characteristics of these samples using mercury porosimetry. The results showed that in the case of PM, porosity was 60%, about three times FP. In addition, we dipped PM samples in water and binder liquid for improving compressive strength by hydration reaction. The compressive strength of two kinds of dipped samples reached about 3 MPa when heated at 90 °C for five hours. Porosity was about 56% when dipped in water, and about 50% when dipped in binder liquid.

AB - In this study, we proposed a powder-layered manufacturing process, which is one technique for rapid prototyping, to produce the desired bone shape for a transplantation from a biomaterial powder. In the experiment, we used conventional inkjet-type equipment and orthopedic filling-paste powder (BIOPEX), of which the main component was alpha-tribasic calcium phosphate, as the forming material. To solidify the powder, we used a sodium chondroitin sulfate + dibasic sodium succinate anhydride aqueous solution-the solvent for mixing powder in clinics-as the binder liquid. In the previous report, we formed a geometric model and living bone to examine the formability of artificial bones, and showed that the formation of artificial bones is possible using this technique. In this paper, we investigated porous characteristics, an important condition for artificial bones. In experiments, we formed cylindrical samples (dimensions:7 mm in diameter, 20 mm in length) by powder-layered manufacturing (PM) and using filling-paste (FP) which is also used in clinical applications. Then we compared the porous characteristics of these samples using mercury porosimetry. The results showed that in the case of PM, porosity was 60%, about three times FP. In addition, we dipped PM samples in water and binder liquid for improving compressive strength by hydration reaction. The compressive strength of two kinds of dipped samples reached about 3 MPa when heated at 90 °C for five hours. Porosity was about 56% when dipped in water, and about 50% when dipped in binder liquid.

KW - Artificial bone

KW - Inkjet

KW - Layered manufacturing

KW - Porosity

KW - Rapid prototyping

UR - http://www.scopus.com/inward/record.url?scp=74049090389&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74049090389&partnerID=8YFLogxK

M3 - Article

VL - 47

SP - 142

EP - 147

JO - BME = Bio medical engineering / henshu, Nihon ME Gakkai

JF - BME = Bio medical engineering / henshu, Nihon ME Gakkai

SN - 1347-443X

IS - 2

ER -