Radical cascade reaction with 1,4-dienes and 1,4-enynes using 2-(iodomethyl)cyclopropane-1,1-dicarboxylate as a homoallyl radical precursor: One-step synthesis of bicyclo[3.3.0]octane derivatives

Osamu Kitagawa, Yoichiro Yamada, Atsushi Sugawara, Takeo Taguchi

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

(equation presented) Radical cascade reaction with various 1,4-dienes and 1,4-enynes using dimethyl 2-(iodomethyl)cyclopropane-1,1-dicarboxylate as a homoallyl radical precursor smoothly proceeds through an iodine atom transfer mechanism to give functionalized bicyclo[3.3.0]octane derivatives in good yields.

Original languageEnglish
Pages (from-to)1011-1013
Number of pages3
JournalOrganic Letters
Volume4
Issue number6
DOIs
Publication statusPublished - 2002 Mar 21
Externally publishedYes

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cyclopropane
octanes
dienes
Iodine
cascades
Derivatives
Atoms
synthesis
iodine
atoms
octane

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Radical cascade reaction with 1,4-dienes and 1,4-enynes using 2-(iodomethyl)cyclopropane-1,1-dicarboxylate as a homoallyl radical precursor : One-step synthesis of bicyclo[3.3.0]octane derivatives. / Kitagawa, Osamu; Yamada, Yoichiro; Sugawara, Atsushi; Taguchi, Takeo.

In: Organic Letters, Vol. 4, No. 6, 21.03.2002, p. 1011-1013.

Research output: Contribution to journalArticle

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abstract = "(equation presented) Radical cascade reaction with various 1,4-dienes and 1,4-enynes using dimethyl 2-(iodomethyl)cyclopropane-1,1-dicarboxylate as a homoallyl radical precursor smoothly proceeds through an iodine atom transfer mechanism to give functionalized bicyclo[3.3.0]octane derivatives in good yields.",
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AU - Taguchi, Takeo

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