Radical induced protein crystallization by radical amplification microfluidic chip

T. Kobayashi, Y. Yamanishi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The paper reports plasma induced radical concentration microfluidic chip and radical induced protein crystallization. The novelty of our work is collection and concentration of radical species and which is confirmed by ESR (Electron Spin Resonance) measurement. Formation of bubbles which has a relatively large surface area accelerates the production of radical species at air-liquid interface and these bubbles are concentrated by the circulating flow in the microfluidic chip. It was also confirmed that the radical-induced protein crystal are produced with increasing of the circulation time. This microfluidic chip contributes to the protein crystal production and bio-medical applications.

Original languageEnglish
Title of host publication2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages700-703
Number of pages4
ISBN (Print)9781479989553
DOIs
Publication statusPublished - 2015 Aug 5
Event18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 - Anchorage, United States
Duration: 2015 Jun 212015 Jun 25

Other

Other18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
CountryUnited States
CityAnchorage
Period15/6/2115/6/25

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Keywords

  • bubble
  • crystallization
  • microfluidic chip
  • Plasma
  • protein
  • radical species

ASJC Scopus subject areas

  • Instrumentation
  • Electrical and Electronic Engineering

Cite this

Kobayashi, T., & Yamanishi, Y. (2015). Radical induced protein crystallization by radical amplification microfluidic chip. In 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 (pp. 700-703). [7181019] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2015.7181019