Rare earth metal ions for unprecedentedly fast RNA hydrolysis.

K. Matsumura; Y. Matsumoto; M. Komiyama

Rare earth metal ions for unprecedentedly fast RNA hydrolysis.

K. Matsumura, Y. Matsumoto, M. Komiyama

Research output: Contribution to journal › Article › peer-review

Abstract

Adenylyl(3'-5')adenosine (ApA) and uridyl(3'-5')uridine (UpU) are hydrolyzed at unprecedentedly large rates by rare earth metal ions at pH 8, 30 degrees C. With 0.01 M Tm(III), the half-lives are 10 min and 51 min, respectively. Potentiality of these ions as catalytic center of artificial ribonuclease is proposed.

Original language	English
Pages (from-to)	11-12
Number of pages	2
Journal	Nucleic acids symposium series
Issue number	27
Publication status	Published - 1992
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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title = "Rare earth metal ions for unprecedentedly fast RNA hydrolysis.",

abstract = "Adenylyl(3'-5')adenosine (ApA) and uridyl(3'-5')uridine (UpU) are hydrolyzed at unprecedentedly large rates by rare earth metal ions at pH 8, 30 degrees C. With 0.01 M Tm(III), the half-lives are 10 min and 51 min, respectively. Potentiality of these ions as catalytic center of artificial ribonuclease is proposed.",

author = "K. Matsumura and Y. Matsumoto and M. Komiyama",

year = "1992",

language = "English",

pages = "11--12",

journal = "Nucleic acids symposium series",

issn = "0261-3166",

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AU - Matsumura, K.

AU - Matsumoto, Y.

AU - Komiyama, M.

PY - 1992

Y1 - 1992

N2 - Adenylyl(3'-5')adenosine (ApA) and uridyl(3'-5')uridine (UpU) are hydrolyzed at unprecedentedly large rates by rare earth metal ions at pH 8, 30 degrees C. With 0.01 M Tm(III), the half-lives are 10 min and 51 min, respectively. Potentiality of these ions as catalytic center of artificial ribonuclease is proposed.

AB - Adenylyl(3'-5')adenosine (ApA) and uridyl(3'-5')uridine (UpU) are hydrolyzed at unprecedentedly large rates by rare earth metal ions at pH 8, 30 degrees C. With 0.01 M Tm(III), the half-lives are 10 min and 51 min, respectively. Potentiality of these ions as catalytic center of artificial ribonuclease is proposed.

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M3 - Article

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AN - SCOPUS:0027025653

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EP - 12

JO - Nucleic acids symposium series

JF - Nucleic acids symposium series

SN - 0261-3166

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ER -

Rare earth metal ions for unprecedentedly fast RNA hydrolysis.

Abstract

ASJC Scopus subject areas

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