Abstract
Adenylyl(3'-5')adenosine (ApA) and uridyl(3'-5')uridine (UpU) are hydrolyzed at unprecedentedly large rates by rare earth metal ions at pH 8, 30 degrees C. With 0.01 M Tm(III), the half-lives are 10 min and 51 min, respectively. Potentiality of these ions as catalytic center of artificial ribonuclease is proposed.
| Original language | English |
|---|---|
| Pages (from-to) | 11-12 |
| Number of pages | 2 |
| Journal | Nucleic acids symposium series |
| Issue number | 27 |
| Publication status | Published - 1992 |
| Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)
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Cite this
Matsumura, K., Matsumoto, Y., & Komiyama, M. (1992). Rare earth metal ions for unprecedentedly fast RNA hydrolysis. Nucleic acids symposium series, (27), 11-12.