Scattering suppression in cylindrical turbid medium for transcutaneous fluorescent imaging through animal tissue

Hirotaka Sasaki; Daiki Ogawa; Takeshi Namita; Yuji Kato; Koichi Shimizu

doi:10.11239/jsmbe.52.O-148

Scattering suppression in cylindrical turbid medium for transcutaneous fluorescent imaging through animal tissue

Hirotaka Sasaki, Daiki Ogawa, Takeshi Namita, Yuji Kato, Koichi Shimizu

Research output: Contribution to journal › Article › peer-review

Abstract

To improve the transcutaneous fluorescent image of an animal body, we derived a point-spread function (PSF) at a cylindrical surface of a turbid medium. In this technique, distortion problem of the restored shape remained. For this problem, new scattering suppression technique using the PSFs divided into the symmetric and asymmetric components was developed. The usefulness of the proposed technique was examined in experiment with biological tissue. The internal fluorescent object, which was hardly seen in the image from observed images, became visible by the proposed technique. Through this analysis, the applicability of the proposed technique to biological tissues was verified.

Original language	English
Pages (from-to)	O-148-O-149
Journal	Transactions of Japanese Society for Medical and Biological Engineering
Volume	52
DOIs	https://doi.org/10.11239/jsmbe.52.O-148
Publication status	Published - 2014 Aug 17
Externally published	Yes

Keywords

3-dimentional reconstruction
Deconvolution
Fluorescent imaging
Point-spread function (PSF)

ASJC Scopus subject areas

Biomedical Engineering

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10.11239/jsmbe.52.O-148

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abstract = "To improve the transcutaneous fluorescent image of an animal body, we derived a point-spread function (PSF) at a cylindrical surface of a turbid medium. In this technique, distortion problem of the restored shape remained. For this problem, new scattering suppression technique using the PSFs divided into the symmetric and asymmetric components was developed. The usefulness of the proposed technique was examined in experiment with biological tissue. The internal fluorescent object, which was hardly seen in the image from observed images, became visible by the proposed technique. Through this analysis, the applicability of the proposed technique to biological tissues was verified.",

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T1 - Scattering suppression in cylindrical turbid medium for transcutaneous fluorescent imaging through animal tissue

AU - Sasaki, Hirotaka

AU - Ogawa, Daiki

AU - Namita, Takeshi

AU - Kato, Yuji

AU - Shimizu, Koichi

PY - 2014/8/17

Y1 - 2014/8/17

N2 - To improve the transcutaneous fluorescent image of an animal body, we derived a point-spread function (PSF) at a cylindrical surface of a turbid medium. In this technique, distortion problem of the restored shape remained. For this problem, new scattering suppression technique using the PSFs divided into the symmetric and asymmetric components was developed. The usefulness of the proposed technique was examined in experiment with biological tissue. The internal fluorescent object, which was hardly seen in the image from observed images, became visible by the proposed technique. Through this analysis, the applicability of the proposed technique to biological tissues was verified.

AB - To improve the transcutaneous fluorescent image of an animal body, we derived a point-spread function (PSF) at a cylindrical surface of a turbid medium. In this technique, distortion problem of the restored shape remained. For this problem, new scattering suppression technique using the PSFs divided into the symmetric and asymmetric components was developed. The usefulness of the proposed technique was examined in experiment with biological tissue. The internal fluorescent object, which was hardly seen in the image from observed images, became visible by the proposed technique. Through this analysis, the applicability of the proposed technique to biological tissues was verified.

KW - 3-dimentional reconstruction

KW - Deconvolution

KW - Fluorescent imaging

KW - Point-spread function (PSF)

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Scattering suppression in cylindrical turbid medium for transcutaneous fluorescent imaging through animal tissue

Abstract

Keywords

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