Selective recognition of 2,4-dichlorophenoxyacetic acid using a molecularly imprinted polymer

Yoko Nomura, Hitoshi Muguruma, Kazuyoshi Yano, Akimitsu Kugimiya, Scott McNiven, Kazunori Ikebukuro, Isao Karube

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


2,4-dichlorophenoxyacetic acid (2,4-D) is a widely used herbicide, but environmental contamination by 2,4-D is problematic. Although biosensors for 2,4-D detection have been investigated, 2,4-D binding proteins and antibodies are too unstable to be used as biosensor recognition elements. In this study, a synthetic polymer selective for 2,4-D was prepared by molecular imprinting, and the binding characteristics of 2,4-D imprinted polymers were examined. Selectivity for 2,4-D was realized using methacrylic acid (MAA) as a functional monomer and the polymer may be used in a 2,4-D sensor.

Original languageEnglish
Pages (from-to)973-980
Number of pages8
JournalAnalytical Letters
Issue number6
Publication statusPublished - 1998
Externally publishedYes


  • 2,4-dichlorophenoxyacetic acid (2,4-D)
  • Herbicide
  • Molecular imprinting

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Spectroscopy
  • Clinical Biochemistry
  • Biochemistry, medical
  • Electrochemistry


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