Self-assembled monolayers of heme derivatives on a gold surface

Kazutoshi Kobayashi, Shinichiro Imabayashi, Katsuhiko Fujita, Kazuhide Nonaka, Takashi Kakiuchi, Hiroyuki Sasabe, Wolfgang Knoll

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Thiolated heme derivatives were synthesized and their self-assembly behaviors on gold surfaces together with that of native heme were studied. The kinetics of this adsorption and the thickness of the formed monolayer were investigated by surface plasmon resonance spectroscopy. Native heme shows a different adsorption behavior compared to that of the synthesized derivatives. Though the heme derivatives were found to form monolayers, native heme formed only irregular aggregates on gold surfaces. IR spectroscopy was used to reveal the molecular structure of the adsorbates in the vicinity of the peptide linkage in the heme molecules on the gold surfaces. UV spectroscopy was employed to determine the tilt angle of the porphyrin rings relative to the gold surface normal. Cyclic voltammograms and potential-modulated UV-vis reflectance spectra of heme derivatives were observed in order to estimate the adsorbed amount and the redox behaviors of heme derivatives on gold surfaces.

Original languageEnglish
Pages (from-to)1993-2000
Number of pages8
JournalBulletin of the Chemical Society of Japan
Volume73
Issue number9
DOIs
Publication statusPublished - 2000 Sep
Externally publishedYes

Fingerprint

Self assembled monolayers
Heme
Gold
Derivatives
Monolayers
Adsorption
Porphyrins
Surface plasmon resonance
Adsorbates
Ultraviolet spectroscopy
Self assembly
Molecular structure
Infrared spectroscopy
Spectroscopy
Peptides
Molecules
Kinetics

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Kobayashi, K., Imabayashi, S., Fujita, K., Nonaka, K., Kakiuchi, T., Sasabe, H., & Knoll, W. (2000). Self-assembled monolayers of heme derivatives on a gold surface. Bulletin of the Chemical Society of Japan, 73(9), 1993-2000. https://doi.org/10.1246/bcsj.73.1993

Self-assembled monolayers of heme derivatives on a gold surface. / Kobayashi, Kazutoshi; Imabayashi, Shinichiro; Fujita, Katsuhiko; Nonaka, Kazuhide; Kakiuchi, Takashi; Sasabe, Hiroyuki; Knoll, Wolfgang.

In: Bulletin of the Chemical Society of Japan, Vol. 73, No. 9, 09.2000, p. 1993-2000.

Research output: Contribution to journalArticle

Kobayashi, K, Imabayashi, S, Fujita, K, Nonaka, K, Kakiuchi, T, Sasabe, H & Knoll, W 2000, 'Self-assembled monolayers of heme derivatives on a gold surface', Bulletin of the Chemical Society of Japan, vol. 73, no. 9, pp. 1993-2000. https://doi.org/10.1246/bcsj.73.1993
Kobayashi, Kazutoshi ; Imabayashi, Shinichiro ; Fujita, Katsuhiko ; Nonaka, Kazuhide ; Kakiuchi, Takashi ; Sasabe, Hiroyuki ; Knoll, Wolfgang. / Self-assembled monolayers of heme derivatives on a gold surface. In: Bulletin of the Chemical Society of Japan. 2000 ; Vol. 73, No. 9. pp. 1993-2000.
@article{da7e239deb5c4f49bb783392f9d56e9f,
title = "Self-assembled monolayers of heme derivatives on a gold surface",
abstract = "Thiolated heme derivatives were synthesized and their self-assembly behaviors on gold surfaces together with that of native heme were studied. The kinetics of this adsorption and the thickness of the formed monolayer were investigated by surface plasmon resonance spectroscopy. Native heme shows a different adsorption behavior compared to that of the synthesized derivatives. Though the heme derivatives were found to form monolayers, native heme formed only irregular aggregates on gold surfaces. IR spectroscopy was used to reveal the molecular structure of the adsorbates in the vicinity of the peptide linkage in the heme molecules on the gold surfaces. UV spectroscopy was employed to determine the tilt angle of the porphyrin rings relative to the gold surface normal. Cyclic voltammograms and potential-modulated UV-vis reflectance spectra of heme derivatives were observed in order to estimate the adsorbed amount and the redox behaviors of heme derivatives on gold surfaces.",
author = "Kazutoshi Kobayashi and Shinichiro Imabayashi and Katsuhiko Fujita and Kazuhide Nonaka and Takashi Kakiuchi and Hiroyuki Sasabe and Wolfgang Knoll",
year = "2000",
month = "9",
doi = "10.1246/bcsj.73.1993",
language = "English",
volume = "73",
pages = "1993--2000",
journal = "Bulletin of the Chemical Society of Japan",
issn = "0009-2673",
publisher = "Chemical Society of Japan",
number = "9",

}

TY - JOUR

T1 - Self-assembled monolayers of heme derivatives on a gold surface

AU - Kobayashi, Kazutoshi

AU - Imabayashi, Shinichiro

AU - Fujita, Katsuhiko

AU - Nonaka, Kazuhide

AU - Kakiuchi, Takashi

AU - Sasabe, Hiroyuki

AU - Knoll, Wolfgang

PY - 2000/9

Y1 - 2000/9

N2 - Thiolated heme derivatives were synthesized and their self-assembly behaviors on gold surfaces together with that of native heme were studied. The kinetics of this adsorption and the thickness of the formed monolayer were investigated by surface plasmon resonance spectroscopy. Native heme shows a different adsorption behavior compared to that of the synthesized derivatives. Though the heme derivatives were found to form monolayers, native heme formed only irregular aggregates on gold surfaces. IR spectroscopy was used to reveal the molecular structure of the adsorbates in the vicinity of the peptide linkage in the heme molecules on the gold surfaces. UV spectroscopy was employed to determine the tilt angle of the porphyrin rings relative to the gold surface normal. Cyclic voltammograms and potential-modulated UV-vis reflectance spectra of heme derivatives were observed in order to estimate the adsorbed amount and the redox behaviors of heme derivatives on gold surfaces.

AB - Thiolated heme derivatives were synthesized and their self-assembly behaviors on gold surfaces together with that of native heme were studied. The kinetics of this adsorption and the thickness of the formed monolayer were investigated by surface plasmon resonance spectroscopy. Native heme shows a different adsorption behavior compared to that of the synthesized derivatives. Though the heme derivatives were found to form monolayers, native heme formed only irregular aggregates on gold surfaces. IR spectroscopy was used to reveal the molecular structure of the adsorbates in the vicinity of the peptide linkage in the heme molecules on the gold surfaces. UV spectroscopy was employed to determine the tilt angle of the porphyrin rings relative to the gold surface normal. Cyclic voltammograms and potential-modulated UV-vis reflectance spectra of heme derivatives were observed in order to estimate the adsorbed amount and the redox behaviors of heme derivatives on gold surfaces.

UR - http://www.scopus.com/inward/record.url?scp=0033801721&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033801721&partnerID=8YFLogxK

U2 - 10.1246/bcsj.73.1993

DO - 10.1246/bcsj.73.1993

M3 - Article

VL - 73

SP - 1993

EP - 2000

JO - Bulletin of the Chemical Society of Japan

JF - Bulletin of the Chemical Society of Japan

SN - 0009-2673

IS - 9

ER -