Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters: A quantitative study with two-photon excitation

Hamza Al Kindi, Ahmed Mohamed, Shinji Kajimoto, Nurbosyn Zhanpeisov, Hideyuki Horino, Yutaka Shibata, Izabela Irena Rzeznicka, Hiroshi Fukumura

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Two-photon luminescence properties of gold nanoclusters (Au8NCs) encapsulated in bovine serum albumin (BSA) were investigated. A new synthesis protocol is reported to control the number of Au8 clusters in one BSA. Both one- and two-photon excitation of BSA with multiple Au8NCs gave an identical blue luminescence. The two-photon absorption (TPA) cross-section value for BSA with one Au8NCs was obtained to be 190 GM (Goeppert-Mayer) and 540 GM for BSA with three Au8NCs, at 740 nm excitation wavelength. This study shows that BSA with multiple Au8NCs may be used as a biocompatible luminescence probe for two-photon in-vivo imaging.

Original languageEnglish
Pages (from-to)168-174
Number of pages7
JournalJournal of Photochemistry and Photobiology A: Chemistry
Volume357
DOIs
Publication statusPublished - 2018 Apr 15

Fingerprint

Nanoclusters
Bovine Serum Albumin
nanoclusters
albumins
Gold
serums
Photons
gold
Molecules
photons
Luminescence
excitation
molecules
luminescence
absorption cross sections
Imaging techniques
Wavelength
probes
synthesis
wavelengths

Keywords

  • Au8 nanocluster
  • Blue emission
  • Bovine serum albumin
  • In-vivo imaging
  • Two-photon absorption
  • Two-photon emission cross-section

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Physics and Astronomy(all)

Cite this

Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters : A quantitative study with two-photon excitation. / Kindi, Hamza Al; Mohamed, Ahmed; Kajimoto, Shinji; Zhanpeisov, Nurbosyn; Horino, Hideyuki; Shibata, Yutaka; Rzeznicka, Izabela Irena; Fukumura, Hiroshi.

In: Journal of Photochemistry and Photobiology A: Chemistry, Vol. 357, 15.04.2018, p. 168-174.

Research output: Contribution to journalArticle

Kindi, Hamza Al ; Mohamed, Ahmed ; Kajimoto, Shinji ; Zhanpeisov, Nurbosyn ; Horino, Hideyuki ; Shibata, Yutaka ; Rzeznicka, Izabela Irena ; Fukumura, Hiroshi. / Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters : A quantitative study with two-photon excitation. In: Journal of Photochemistry and Photobiology A: Chemistry. 2018 ; Vol. 357. pp. 168-174.
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AU - Horino, Hideyuki

AU - Shibata, Yutaka

AU - Rzeznicka, Izabela Irena

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