Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters: A quantitative study with two-photon excitation

Hamza Al Kindi; Ahmed Mohamed; Shinji Kajimoto; Nurbosyn Zhanpeisov; Hideyuki Horino; Yutaka Shibata; Izabela I. Rzeznicka; Hiroshi Fukumura

doi:10.1016/j.jphotochem.2018.02.029

Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters: A quantitative study with two-photon excitation

Hamza Al Kindi, Ahmed Mohamed, Shinji Kajimoto, Nurbosyn Zhanpeisov, Hideyuki Horino, Yutaka Shibata, Izabela I. Rzeznicka, Hiroshi Fukumura

Global course of Engineering and Science

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Two-photon luminescence properties of gold nanoclusters (Au₈NCs) encapsulated in bovine serum albumin (BSA) were investigated. A new synthesis protocol is reported to control the number of Au₈ clusters in one BSA. Both one- and two-photon excitation of BSA with multiple Au₈NCs gave an identical blue luminescence. The two-photon absorption (TPA) cross-section value for BSA with one Au₈NCs was obtained to be 190 GM (Goeppert-Mayer) and 540 GM for BSA with three Au₈NCs, at 740 nm excitation wavelength. This study shows that BSA with multiple Au₈NCs may be used as a biocompatible luminescence probe for two-photon in-vivo imaging.

Original language	English
Pages (from-to)	168-174
Number of pages	7
Journal	Journal of Photochemistry and Photobiology A: Chemistry
Volume	357
DOIs	https://doi.org/10.1016/j.jphotochem.2018.02.029
Publication status	Published - 2018 Apr 15

Keywords

Au8 nanocluster
Blue emission
Bovine serum albumin
In-vivo imaging
Two-photon absorption
Two-photon emission cross-section

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)
Physics and Astronomy(all)

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10.1016/j.jphotochem.2018.02.029

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Kindi, H. A., Mohamed, A., Kajimoto, S., Zhanpeisov, N., Horino, H., Shibata, Y., Rzeznicka, I. I., & Fukumura, H. (2018). Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters: A quantitative study with two-photon excitation. Journal of Photochemistry and Photobiology A: Chemistry, 357, 168-174. https://doi.org/10.1016/j.jphotochem.2018.02.029

Kindi, HA, Mohamed, A, Kajimoto, S, Zhanpeisov, N, Horino, H, Shibata, Y, Rzeznicka, II & Fukumura, H 2018, 'Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters: A quantitative study with two-photon excitation', Journal of Photochemistry and Photobiology A: Chemistry, vol. 357, pp. 168-174. https://doi.org/10.1016/j.jphotochem.2018.02.029

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title = "Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters: A quantitative study with two-photon excitation",

abstract = "Two-photon luminescence properties of gold nanoclusters (Au8NCs) encapsulated in bovine serum albumin (BSA) were investigated. A new synthesis protocol is reported to control the number of Au8 clusters in one BSA. Both one- and two-photon excitation of BSA with multiple Au8NCs gave an identical blue luminescence. The two-photon absorption (TPA) cross-section value for BSA with one Au8NCs was obtained to be 190 GM (Goeppert-Mayer) and 540 GM for BSA with three Au8NCs, at 740 nm excitation wavelength. This study shows that BSA with multiple Au8NCs may be used as a biocompatible luminescence probe for two-photon in-vivo imaging.",

keywords = "Au8 nanocluster, Blue emission, Bovine serum albumin, In-vivo imaging, Two-photon absorption, Two-photon emission cross-section",

author = "Kindi, {Hamza Al} and Ahmed Mohamed and Shinji Kajimoto and Nurbosyn Zhanpeisov and Hideyuki Horino and Yutaka Shibata and Rzeznicka, {Izabela I.} and Hiroshi Fukumura",

note = "Funding Information: The authors acknowledge Shun Ito of Institute of Materials Research, Tohoku University for taking TEM images. IIR thanks for a start-up grant from Shibaura Institute of Technology. Publisher Copyright: {\textcopyright} 2018 Elsevier B.V. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",

year = "2018",

month = apr,

day = "15",

doi = "10.1016/j.jphotochem.2018.02.029",

language = "English",

volume = "357",

pages = "168--174",

journal = "Journal of Photochemistry and Photobiology A: Chemistry",

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T1 - Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters

T2 - A quantitative study with two-photon excitation

AU - Kindi, Hamza Al

AU - Mohamed, Ahmed

AU - Kajimoto, Shinji

AU - Zhanpeisov, Nurbosyn

AU - Horino, Hideyuki

AU - Shibata, Yutaka

AU - Rzeznicka, Izabela I.

AU - Fukumura, Hiroshi

N1 - Funding Information: The authors acknowledge Shun Ito of Institute of Materials Research, Tohoku University for taking TEM images. IIR thanks for a start-up grant from Shibaura Institute of Technology. Publisher Copyright: © 2018 Elsevier B.V. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

PY - 2018/4/15

Y1 - 2018/4/15

N2 - Two-photon luminescence properties of gold nanoclusters (Au8NCs) encapsulated in bovine serum albumin (BSA) were investigated. A new synthesis protocol is reported to control the number of Au8 clusters in one BSA. Both one- and two-photon excitation of BSA with multiple Au8NCs gave an identical blue luminescence. The two-photon absorption (TPA) cross-section value for BSA with one Au8NCs was obtained to be 190 GM (Goeppert-Mayer) and 540 GM for BSA with three Au8NCs, at 740 nm excitation wavelength. This study shows that BSA with multiple Au8NCs may be used as a biocompatible luminescence probe for two-photon in-vivo imaging.

AB - Two-photon luminescence properties of gold nanoclusters (Au8NCs) encapsulated in bovine serum albumin (BSA) were investigated. A new synthesis protocol is reported to control the number of Au8 clusters in one BSA. Both one- and two-photon excitation of BSA with multiple Au8NCs gave an identical blue luminescence. The two-photon absorption (TPA) cross-section value for BSA with one Au8NCs was obtained to be 190 GM (Goeppert-Mayer) and 540 GM for BSA with three Au8NCs, at 740 nm excitation wavelength. This study shows that BSA with multiple Au8NCs may be used as a biocompatible luminescence probe for two-photon in-vivo imaging.

KW - Au8 nanocluster

KW - Blue emission

KW - Bovine serum albumin

KW - In-vivo imaging

KW - Two-photon absorption

KW - Two-photon emission cross-section

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JO - Journal of Photochemistry and Photobiology A: Chemistry

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Single bovine serum albumin molecule can hold plural blue-emissive gold nanoclusters: A quantitative study with two-photon excitation

Abstract

Keywords

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