Size-dependent filtration and trap of microparticles using centrifugal force and graduated mechanical gap in microfluidic chip

Hisataka Maruyama, Shinya Sakuma, Yoko Yamanishi, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We proposed size-dependent microparticle filtration and particle trap by centrifugal force and mechanical restriction in a microfluidic chip. Novelties of this paper are summarized as follows. (1) Filtration is robust against pressure fluctuation in microchannels, (2) Clogging of microparticles is avoided by rotation of threedimensional magnetically driven microtool (3D-MMT), (3) Size-classified microparticles can be trapped in microchannels by flow control. Microparticles having different sizes flow in circular microchannels and filtered according to their sizes by gaps between sidewalls and substrate by centrifugal force. Rotation of 3D-MMT by external magnetic force generates swirling flow in microchamber. Size-classified microparticles can be trapped in microchannel by flow control. We demonstrated filtration and trap of microparticles in a chip.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1479-1481
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - 2009 Jan 1
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 2009 Nov 12009 Nov 5

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period09/11/109/11/5

Keywords

  • Centrifugal force
  • Filtration
  • Magnetic force
  • Particle
  • Trapping

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Maruyama, H., Sakuma, S., Yamanishi, Y., & Arai, F. (2009). Size-dependent filtration and trap of microparticles using centrifugal force and graduated mechanical gap in microfluidic chip. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1479-1481). (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.