Slide-ring materials

New polymeric materials for dds

Masatoshi Kidowaki, Kohzo Ito, Tohiyuki Kataoka, Masatoshi Kidowaki, Kohzo Ito

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We reviewed the fundamental aspects and applications of slide-ring materials as new polymeric materials for DDS. The slide-ring gel is one of the slide-ring materials using sliding features most effectively and has movable cross-linking junctions. As a result, it exhibited mechanical properties quite different from chemical gels, rather close to biomaterials. The small angle neutron scattering studies of the slide-ring gels revealed that the pulley effect relaxed the inhomogeneous structure in the slide-ring gels. In addition, we introduced the sol-gel transition of methylated polyrotaxane as a new thermoreversible DDS system. Finally, we discussed the application of the slide-ring materials to DDS with the future view.

Original languageEnglish
Pages (from-to)592-598
Number of pages7
JournalDrug Delivery System
Volume21
Issue number6
DOIs
Publication statusPublished - 2006
Externally publishedYes

Keywords

  • polyrotaxane
  • slide-ring gel
  • thermo-reversible sol-gel transition

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Slide-ring materials : New polymeric materials for dds. / Kidowaki, Masatoshi; Ito, Kohzo; Kataoka, Tohiyuki; Kidowaki, Masatoshi; Ito, Kohzo.

In: Drug Delivery System, Vol. 21, No. 6, 2006, p. 592-598.

Research output: Contribution to journalArticle

Kidowaki, M, Ito, K, Kataoka, T, Kidowaki, M & Ito, K 2006, 'Slide-ring materials: New polymeric materials for dds', Drug Delivery System, vol. 21, no. 6, pp. 592-598. https://doi.org/10.2745/dds.21.592
Kidowaki, Masatoshi ; Ito, Kohzo ; Kataoka, Tohiyuki ; Kidowaki, Masatoshi ; Ito, Kohzo. / Slide-ring materials : New polymeric materials for dds. In: Drug Delivery System. 2006 ; Vol. 21, No. 6. pp. 592-598.
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