Abstract
We succeeded in automation of removal of the zona pellucida of swine oocyte using magnetically driven microtool (MMT) in microfluidic chip. The proposed system can manipulate multiple oocytes at one time with high stability which has an strong advantages over the conventional manual manipulation of removal one by one with pipetting. We proposed the automation of removal of zona pellucida by activating soft polymeric materials in a disposable microfluidic chip to achieve mass production of manipulated embryos as well as accurate and stable manipulations. It can be a breakthrough of a high throughput of accurate and effective oocyte manipulations in the field of cloning and fertility treatment.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) |
| Pages | 256-259 |
| Number of pages | 4 |
| DOIs | |
| Publication status | Published - 2010 |
| Externally published | Yes |
| Event | 23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010 - Hong Kong Duration: 2010 Jan 24 → 2010 Jan 28 |
Other
| Other | 23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010 |
|---|---|
| City | Hong Kong |
| Period | 10/1/24 → 10/1/28 |
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ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Mechanical Engineering
- Condensed Matter Physics
- Electronic, Optical and Magnetic Materials
Cite this
Soft scrubbing off of zona pellucida on disposable microfluidic chip. / Yamanishi, Yoko; Mizunuma, Takehito; Inomata, Naoki; Kudo, Shogo; Arai, Funihito.
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010. p. 256-259 5442516.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Soft scrubbing off of zona pellucida on disposable microfluidic chip
AU - Yamanishi, Yoko
AU - Mizunuma, Takehito
AU - Inomata, Naoki
AU - Kudo, Shogo
AU - Arai, Funihito
PY - 2010
Y1 - 2010
N2 - We succeeded in automation of removal of the zona pellucida of swine oocyte using magnetically driven microtool (MMT) in microfluidic chip. The proposed system can manipulate multiple oocytes at one time with high stability which has an strong advantages over the conventional manual manipulation of removal one by one with pipetting. We proposed the automation of removal of zona pellucida by activating soft polymeric materials in a disposable microfluidic chip to achieve mass production of manipulated embryos as well as accurate and stable manipulations. It can be a breakthrough of a high throughput of accurate and effective oocyte manipulations in the field of cloning and fertility treatment.
AB - We succeeded in automation of removal of the zona pellucida of swine oocyte using magnetically driven microtool (MMT) in microfluidic chip. The proposed system can manipulate multiple oocytes at one time with high stability which has an strong advantages over the conventional manual manipulation of removal one by one with pipetting. We proposed the automation of removal of zona pellucida by activating soft polymeric materials in a disposable microfluidic chip to achieve mass production of manipulated embryos as well as accurate and stable manipulations. It can be a breakthrough of a high throughput of accurate and effective oocyte manipulations in the field of cloning and fertility treatment.
UR - http://www.scopus.com/inward/record.url?scp=77952768676&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952768676&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2010.5442516
DO - 10.1109/MEMSYS.2010.5442516
M3 - Conference contribution
AN - SCOPUS:77952768676
SN - 9781424457649
SP - 256
EP - 259
BT - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ER -