Soft scrubbing off of zona pellucida on disposable microfluidic chip

Yoko Yamanishi, Takehito Mizunuma, Naoki Inomata, Shogo Kudo, Funihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Citations (Scopus)

Abstract

We succeeded in automation of removal of the zona pellucida of swine oocyte using magnetically driven microtool (MMT) in microfluidic chip. The proposed system can manipulate multiple oocytes at one time with high stability which has an strong advantages over the conventional manual manipulation of removal one by one with pipetting. We proposed the automation of removal of zona pellucida by activating soft polymeric materials in a disposable microfluidic chip to achieve mass production of manipulated embryos as well as accurate and stable manipulations. It can be a breakthrough of a high throughput of accurate and effective oocyte manipulations in the field of cloning and fertility treatment.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages256-259
Number of pages4
DOIs
Publication statusPublished - 2010
Externally publishedYes
Event23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010 - Hong Kong
Duration: 2010 Jan 242010 Jan 28

Other

Other23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010
CityHong Kong
Period10/1/2410/1/28

Fingerprint

gametocytes
washing
Microfluidics
manipulators
chips
automation
Automation
fertility
swine
Cloning
embryos
Throughput
Polymers

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Yamanishi, Y., Mizunuma, T., Inomata, N., Kudo, S., & Arai, F. (2010). Soft scrubbing off of zona pellucida on disposable microfluidic chip. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 256-259). [5442516] https://doi.org/10.1109/MEMSYS.2010.5442516

Soft scrubbing off of zona pellucida on disposable microfluidic chip. / Yamanishi, Yoko; Mizunuma, Takehito; Inomata, Naoki; Kudo, Shogo; Arai, Funihito.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010. p. 256-259 5442516.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yamanishi, Y, Mizunuma, T, Inomata, N, Kudo, S & Arai, F 2010, Soft scrubbing off of zona pellucida on disposable microfluidic chip. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)., 5442516, pp. 256-259, 23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010, Hong Kong, 10/1/24. https://doi.org/10.1109/MEMSYS.2010.5442516
Yamanishi Y, Mizunuma T, Inomata N, Kudo S, Arai F. Soft scrubbing off of zona pellucida on disposable microfluidic chip. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010. p. 256-259. 5442516 https://doi.org/10.1109/MEMSYS.2010.5442516
Yamanishi, Yoko ; Mizunuma, Takehito ; Inomata, Naoki ; Kudo, Shogo ; Arai, Funihito. / Soft scrubbing off of zona pellucida on disposable microfluidic chip. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010. pp. 256-259
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