Synthesis of aminoglycoside derivatives on a Cbz-type heavy fluorous tag

Mamoru Mizuno, Hiroharu Matsumoto, Kohtaro Goto, Keita Hamasaki

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Four aminoglycoside derivatives containing a 2,6-diamino-2,6-dideoxy-d-glucopyranose disaccharide structure were successfully prepared by using a Cbz-type heavy fluorous tag in a fluorous synthesis. A Cbz-type heavy fluorous tag was prepared using the hexakis(fluorous chain)-type alcohol 11, and the fluorous alcohol 11 was recovered in good yield after the synthesis of aminoglycoside derivatives.

Original languageEnglish
Pages (from-to)8831-8835
Number of pages5
JournalTetrahedron Letters
Issue number50
Publication statusPublished - 2006 Dec 11

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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