Synthesis of Optically Active Atropisomeric Anilide Derivatives through Diastereoselective N-Allylation with a Chiral Pd-π-Allyl Catalyst

Osamu Kitagawa, Masashi Takahashi, Mitsuteru Kohriyama, Takeo Taguchi

Research output: Contribution to journal › Article

7 Citations (Scopus)

Abstract

N-Allylation of o-tert-butyl anilides derived from o-tert-butyl aniline and (S)-lactic acid or (S)-mandelic acid proceeded with high diastereoselectivity in the presence of a (BINAP)Pd-π-allyl catalyst to give atropisomeric N-allyl o-tert-butyl anilide derivatives.

Original languageEnglish
Pages (from-to)9851-9853
Number of pages3
JournalJournal of Organic Chemistry
Volume68
Issue number25
DOIs
Publication statusPublished - 2003 Dec 12
Externally publishedYes

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Anilides
Allylation
Derivatives
Catalysts
Lactic Acid

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of Optically Active Atropisomeric Anilide Derivatives through Diastereoselective N-Allylation with a Chiral Pd-π-Allyl Catalyst. / Kitagawa, Osamu; Takahashi, Masashi; Kohriyama, Mitsuteru; Taguchi, Takeo.

In: Journal of Organic Chemistry, Vol. 68, No. 25, 12.12.2003, p. 9851-9853.

Research output: Contribution to journal › Article

Kitagawa, O, Takahashi, M, Kohriyama, M & Taguchi, T 2003, 'Synthesis of Optically Active Atropisomeric Anilide Derivatives through Diastereoselective N-Allylation with a Chiral Pd-π-Allyl Catalyst', Journal of Organic Chemistry, vol. 68, no. 25, pp. 9851-9853. https://doi.org/10.1021/jo035305l
Kitagawa O, Takahashi M, Kohriyama M, Taguchi T. Synthesis of Optically Active Atropisomeric Anilide Derivatives through Diastereoselective N-Allylation with a Chiral Pd-π-Allyl Catalyst. Journal of Organic Chemistry. 2003 Dec 12;68(25):9851-9853. https://doi.org/10.1021/jo035305l
Kitagawa, Osamu ; Takahashi, Masashi ; Kohriyama, Mitsuteru ; Taguchi, Takeo. / Synthesis of Optically Active Atropisomeric Anilide Derivatives through Diastereoselective N-Allylation with a Chiral Pd-π-Allyl Catalyst. In: Journal of Organic Chemistry. 2003 ; Vol. 68, No. 25. pp. 9851-9853.
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