TY - JOUR
T1 - THz imaging of nucleobases and cancerous tissue using a GaP THz-wave generator
AU - Nishizawa, Jun Ichi
AU - Sasaki, Tetsuo
AU - Suto, Ken
AU - Yamada, Tetsuya
AU - Tanabe, Tadao
AU - Tanno, Takenori
AU - Sawai, Takashi
AU - Miura, Yasuhiro
N1 - Funding Information:
We thank Prof. M. Watanabe, Iwate Prefectural University, for making valuable suggestions. This study was conducted as part of the Terahertz Optics Project for Medical Applications led by J. Nishizawa, organized by the Ministry of Education, Culture, Sports, Science, and Technology, of Japan. The authors thank H. Watanabe and T. Kimura for constructing the system.
Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/1/3
Y1 - 2005/1/3
N2 - We constructed a terahertz (THz) spectroscopic imaging system using a GaP THz-wave generator with automatic scanning control, and demonstrated power-transmission imaging measurements. To characterize the system, images of polyethylene pellets containing cytosine powder at various concentrations were taken. At a resonance frequency of 2.86 THz, the imaging system detected 5000 ppm cytosine. In addition, we demonstrated that THz imaging has a possibility to distinguish regions of metastatic cancer from normal tissue in liver, by comparing a THz-wave image at 0.835 THz with that at 1.465 THz.
AB - We constructed a terahertz (THz) spectroscopic imaging system using a GaP THz-wave generator with automatic scanning control, and demonstrated power-transmission imaging measurements. To characterize the system, images of polyethylene pellets containing cytosine powder at various concentrations were taken. At a resonance frequency of 2.86 THz, the imaging system detected 5000 ppm cytosine. In addition, we demonstrated that THz imaging has a possibility to distinguish regions of metastatic cancer from normal tissue in liver, by comparing a THz-wave image at 0.835 THz with that at 1.465 THz.
KW - Cancer liver
KW - Cytosine
KW - Frequency-tunable coherent terahertz wave
KW - Terahertz imaging
KW - Terahertz spectroscopy
UR - http://www.scopus.com/inward/record.url?scp=10844287060&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=10844287060&partnerID=8YFLogxK
U2 - 10.1016/j.optcom.2004.09.064
DO - 10.1016/j.optcom.2004.09.064
M3 - Article
AN - SCOPUS:10844287060
VL - 244
SP - 469
EP - 474
JO - Optics Communications
JF - Optics Communications
SN - 0030-4018
IS - 1-6
ER -