We focus on a region-based point clustering to extract a polygon from a massive point cloud. In the region-based clustering, RANSAC is a suitable approach for estimating surfaces. However, local workspace selection is required to improve a performance in a surface estimation from a massive point cloud. Moreover, the conventional RANSAC is hard to determine whether a point lies inside or outside a surface. In this paper, we propose a method for panoramic rendering-based polygon extraction from indoor mobile LiDAR data. Our aim was to improve region-based point cloud clustering in modeling after point cloud registration. First, we propose a point cloud clustering methodology for polygon extraction on a panoramic range image generated with point-based rendering from a massive point cloud. Next, we describe an experiment that was conducted to verify our methodology with an indoor mobile mapping system in an indoor environment. This experiment was wall-surface extraction using a rendered point cloud from some viewpoints over a wide indoor area. Finally, we confirmed that our proposed methodology could achieve polygon extraction through point cloud clustering from a complex indoor environment.