TY - JOUR
T1 - Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA.
AU - Matsumura, K.
AU - Kina, S.
AU - Sumaoka, J.
AU - Tobey, S.
AU - Anslyn, E. V.
AU - Komiyama, M.
PY - 2001
Y1 - 2001
N2 - Trinuclear Cu(II) complex of N,N,N',N',N",N"-hexa[(2-pyridyl)methyl]-1,3,5-tris(aminomethyl)benzene (L3A) exhibits remarkable substrate-specificity for hydrolysis of 2'-->5' and 3'-->5' ribonucleotides. Up(2'-->5')U is hydrolyzed much efficiently than is Up(3'-->5')U, but Ap(3'-->5')A is overwhelmingly preferable to Ap(2'-->5')A.
AB - Trinuclear Cu(II) complex of N,N,N',N',N",N"-hexa[(2-pyridyl)methyl]-1,3,5-tris(aminomethyl)benzene (L3A) exhibits remarkable substrate-specificity for hydrolysis of 2'-->5' and 3'-->5' ribonucleotides. Up(2'-->5')U is hydrolyzed much efficiently than is Up(3'-->5')U, but Ap(3'-->5')A is overwhelmingly preferable to Ap(2'-->5')A.
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U2 - 10.1093/nass/1.1.85
DO - 10.1093/nass/1.1.85
M3 - Article
C2 - 12836276
AN - SCOPUS:0042704979
SP - 85
EP - 86
JO - Nucleic acids research. Supplement (2001)
JF - Nucleic acids research. Supplement (2001)
IS - 1
ER -