Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA.

Kazunari Matsumura, S. Kina, J. Sumaoka, S. Tobey, E. V. Anslyn, M. Komiyama

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Trinuclear Cu(II) complex of N,N,N',N',N",N"-hexa[(2-pyridyl)methyl]-1,3,5-tris(aminomethyl)benzene (L3A) exhibits remarkable substrate-specificity for hydrolysis of 2'-->5' and 3'-->5' ribonucleotides. Up(2'-->5')U is hydrolyzed much efficiently than is Up(3'-->5')U, but Ap(3'-->5')A is overwhelmingly preferable to Ap(2'-->5')A.

Original languageEnglish
Title of host publicationNucleic acids research. Supplement (2001)
Pages85-86
Number of pages2
Edition1
Publication statusPublished - 2001
Externally publishedYes

Cite this

Matsumura, K., Kina, S., Sumaoka, J., Tobey, S., Anslyn, E. V., & Komiyama, M. (2001). Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA. In Nucleic acids research. Supplement (2001) (1 ed., pp. 85-86)

Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA. / Matsumura, Kazunari; Kina, S.; Sumaoka, J.; Tobey, S.; Anslyn, E. V.; Komiyama, M.

Nucleic acids research. Supplement (2001). 1. ed. 2001. p. 85-86.

Research output: Chapter in Book/Report/Conference proceedingChapter

Matsumura, K, Kina, S, Sumaoka, J, Tobey, S, Anslyn, EV & Komiyama, M 2001, Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA. in Nucleic acids research. Supplement (2001). 1 edn, pp. 85-86.
Matsumura K, Kina S, Sumaoka J, Tobey S, Anslyn EV, Komiyama M. Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA. In Nucleic acids research. Supplement (2001). 1 ed. 2001. p. 85-86
Matsumura, Kazunari ; Kina, S. ; Sumaoka, J. ; Tobey, S. ; Anslyn, E. V. ; Komiyama, M. / Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA. Nucleic acids research. Supplement (2001). 1. ed. 2001. pp. 85-86
@inbook{9a20b74ffd7e4f32b40cd0f54c9fa286,
title = "Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA.",
abstract = "Trinuclear Cu(II) complex of N,N,N',N',N{"},N{"}-hexa[(2-pyridyl)methyl]-1,3,5-tris(aminomethyl)benzene (L3A) exhibits remarkable substrate-specificity for hydrolysis of 2'-->5' and 3'-->5' ribonucleotides. Up(2'-->5')U is hydrolyzed much efficiently than is Up(3'-->5')U, but Ap(3'-->5')A is overwhelmingly preferable to Ap(2'-->5')A.",
author = "Kazunari Matsumura and S. Kina and J. Sumaoka and S. Tobey and Anslyn, {E. V.} and M. Komiyama",
year = "2001",
language = "English",
pages = "85--86",
booktitle = "Nucleic acids research. Supplement (2001)",
edition = "1",

}

TY - CHAP

T1 - Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA.

AU - Matsumura, Kazunari

AU - Kina, S.

AU - Sumaoka, J.

AU - Tobey, S.

AU - Anslyn, E. V.

AU - Komiyama, M.

PY - 2001

Y1 - 2001

N2 - Trinuclear Cu(II) complex of N,N,N',N',N",N"-hexa[(2-pyridyl)methyl]-1,3,5-tris(aminomethyl)benzene (L3A) exhibits remarkable substrate-specificity for hydrolysis of 2'-->5' and 3'-->5' ribonucleotides. Up(2'-->5')U is hydrolyzed much efficiently than is Up(3'-->5')U, but Ap(3'-->5')A is overwhelmingly preferable to Ap(2'-->5')A.

AB - Trinuclear Cu(II) complex of N,N,N',N',N",N"-hexa[(2-pyridyl)methyl]-1,3,5-tris(aminomethyl)benzene (L3A) exhibits remarkable substrate-specificity for hydrolysis of 2'-->5' and 3'-->5' ribonucleotides. Up(2'-->5')U is hydrolyzed much efficiently than is Up(3'-->5')U, but Ap(3'-->5')A is overwhelmingly preferable to Ap(2'-->5')A.

UR - http://www.scopus.com/inward/record.url?scp=0042704979&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0042704979&partnerID=8YFLogxK

M3 - Chapter

SP - 85

EP - 86

BT - Nucleic acids research. Supplement (2001)

ER -