TY - GEN
T1 - Ultrasonic measurement of vascular scaffold elasticity using catheter system
AU - Nitta, N.
AU - Yamane, Takashi
AU - Matsumura, G.
AU - Shiina, Tsuyoshi
PY - 2008
Y1 - 2008
N2 - Characterization of grafted vascular scaffold is essential for evaluating its biocompatibility, maturity and structural intensity. Quantitative elastic modulus measurement of vascular scaffold powerfully assists its characterization because the mechanical property is closely related with the biocompatibility, maturity and structural intensity of the vascular scaffold. We have presented an in vitro or in vivo measurement system for the tissue-engineered vessel before and after grafting in the previous study, we present a novel and modified method for in vivo assessment and follow-up of the vascular scaffold in this study. The measured quantitative elastic modulus is converted into the regeneration score for in vivo assessment. The effectiveness of the proposed evaluation method was validated by in vivo experimental data using canines.
AB - Characterization of grafted vascular scaffold is essential for evaluating its biocompatibility, maturity and structural intensity. Quantitative elastic modulus measurement of vascular scaffold powerfully assists its characterization because the mechanical property is closely related with the biocompatibility, maturity and structural intensity of the vascular scaffold. We have presented an in vitro or in vivo measurement system for the tissue-engineered vessel before and after grafting in the previous study, we present a novel and modified method for in vivo assessment and follow-up of the vascular scaffold in this study. The measured quantitative elastic modulus is converted into the regeneration score for in vivo assessment. The effectiveness of the proposed evaluation method was validated by in vivo experimental data using canines.
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U2 - 10.1109/iembs.2008.4650410
DO - 10.1109/iembs.2008.4650410
M3 - Conference contribution
C2 - 19163913
AN - SCOPUS:61849142203
SN - 9781424418152
T3 - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"
SP - 5298
EP - 5301
BT - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
PB - IEEE Computer Society
T2 - 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Y2 - 20 August 2008 through 25 August 2008
ER -