Using the light scattering component of optical intrinsic signals to visualize in vivo functional structures of neural tissues

Rajagopalan Umamaheswari; Kazushige Tsunoda; Manabu Tanifuji

doi:10.1007/978-1-59745-543-5_6

Using the light scattering component of optical intrinsic signals to visualize in vivo functional structures of neural tissues

Rajagopalan Umamaheswari, Kazushige Tsunoda, Manabu Tanifuji

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Abstract

Visualization of changes in reflected light from in vivo brain tissues reveals spatial patterns of neural activity. An important factor which influences the degree of light reflected includes the change in light scattering elicited by neural activation. Microstructures of neural tissues generally cause light scattering, and neural activities are associated with some changes in the microstructures. Here, we show that the optical properties unique to light scattering enable us to visualize spatial patterns of retinal activity non-invasively (FRG: functional retinography), and resolve functional structures in depth (fOCT: functional optical coherence tomography).

Original language	English
Title of host publication	Dynamic Brain Imaging
Subtitle of host publication	Multi-Modal Methods and In Vivo Applications
Publisher	Humana Press
Pages	111-132
Number of pages	22
ISBN (Print)	9781934115749
DOIs	https://doi.org/10.1007/978-1-59745-543-5_6
Publication status	Published - 2009 Jan 1
Externally published	Yes

Publication series

Name	Methods in Molecular Biology
Volume	489
ISSN (Print)	1064-3745

Keywords

Intrinisic signal imaging
Light scattering
OCT
Optical coherence tomography

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-59745-543-5_6

Cite this

Using the light scattering component of optical intrinsic signals to visualize in vivo functional structures of neural tissues. / Umamaheswari, Rajagopalan; Tsunoda, Kazushige; Tanifuji, Manabu.

Dynamic Brain Imaging: Multi-Modal Methods and In Vivo Applications. Humana Press, 2009. p. 111-132 (Methods in Molecular Biology; Vol. 489).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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Using the light scattering component of optical intrinsic signals to visualize in vivo functional structures of neural tissues

Abstract

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Keywords

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