Water absorption by decellularized dermis

Yongwei Zhang, Takuya Iwata, Kwangwoo Nam, Tsuyoshi Kimura, Pingli Wu, Naoko Nakamura, Yoshihide Hashimoto, Akio Kishida

Research output: Contribution to journalArticle

Abstract

Water absorption by decellularized dermis was investigated and compared with biopolymer and synthetic polymer hydrogels (glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogel, respectively). Porcine dermis was decellularized in an aqueous sodium dodecyl sulfate (SDS) solution. Histological evaluation revealed that the SDS-treated dermis has much larger gaps between collagen fibrils than non-treated dermis, and that water absorption depends on these gaps. Decellularized dermis has low water absorptivity and the absorption obeys Fick's second law. During absorption, the water diffusion rate decreases with time and occurs in two steps. The first is rapid absorption into the large gaps, followed by slow absorption by the collagen fiber layer. Because of the gaps, decellularized dermis can absorb more water than native dermis and shows different water absorption behavior to glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogels.

Original languageEnglish
Article numbere00600
JournalHeliyon
Volume4
Issue number4
DOIs
Publication statusPublished - 2018 Apr 1
Externally publishedYes

Fingerprint

Water absorption
Hydrogels
Glutaral
Gelatin
Polyacrylates
Sodium Dodecyl Sulfate
Water
Collagen
Biopolymers
Hydrogel
Polymers
Fibers

Keywords

  • Bioengineering
  • Materials science

ASJC Scopus subject areas

  • General

Cite this

Zhang, Y., Iwata, T., Nam, K., Kimura, T., Wu, P., Nakamura, N., ... Kishida, A. (2018). Water absorption by decellularized dermis. Heliyon, 4(4), [e00600]. https://doi.org/10.1016/j.heliyon.2018.e00600

Water absorption by decellularized dermis. / Zhang, Yongwei; Iwata, Takuya; Nam, Kwangwoo; Kimura, Tsuyoshi; Wu, Pingli; Nakamura, Naoko; Hashimoto, Yoshihide; Kishida, Akio.

In: Heliyon, Vol. 4, No. 4, e00600, 01.04.2018.

Research output: Contribution to journalArticle

Zhang, Y, Iwata, T, Nam, K, Kimura, T, Wu, P, Nakamura, N, Hashimoto, Y & Kishida, A 2018, 'Water absorption by decellularized dermis', Heliyon, vol. 4, no. 4, e00600. https://doi.org/10.1016/j.heliyon.2018.e00600
Zhang Y, Iwata T, Nam K, Kimura T, Wu P, Nakamura N et al. Water absorption by decellularized dermis. Heliyon. 2018 Apr 1;4(4). e00600. https://doi.org/10.1016/j.heliyon.2018.e00600
Zhang, Yongwei ; Iwata, Takuya ; Nam, Kwangwoo ; Kimura, Tsuyoshi ; Wu, Pingli ; Nakamura, Naoko ; Hashimoto, Yoshihide ; Kishida, Akio. / Water absorption by decellularized dermis. In: Heliyon. 2018 ; Vol. 4, No. 4.
@article{3d392cbcb84e40fca2bb5b1d945a536b,
title = "Water absorption by decellularized dermis",
abstract = "Water absorption by decellularized dermis was investigated and compared with biopolymer and synthetic polymer hydrogels (glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogel, respectively). Porcine dermis was decellularized in an aqueous sodium dodecyl sulfate (SDS) solution. Histological evaluation revealed that the SDS-treated dermis has much larger gaps between collagen fibrils than non-treated dermis, and that water absorption depends on these gaps. Decellularized dermis has low water absorptivity and the absorption obeys Fick's second law. During absorption, the water diffusion rate decreases with time and occurs in two steps. The first is rapid absorption into the large gaps, followed by slow absorption by the collagen fiber layer. Because of the gaps, decellularized dermis can absorb more water than native dermis and shows different water absorption behavior to glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogels.",
keywords = "Bioengineering, Materials science",
author = "Yongwei Zhang and Takuya Iwata and Kwangwoo Nam and Tsuyoshi Kimura and Pingli Wu and Naoko Nakamura and Yoshihide Hashimoto and Akio Kishida",
year = "2018",
month = "4",
day = "1",
doi = "10.1016/j.heliyon.2018.e00600",
language = "English",
volume = "4",
journal = "Heliyon",
issn = "2405-8440",
publisher = "Elsevier BV",
number = "4",

}

TY - JOUR

T1 - Water absorption by decellularized dermis

AU - Zhang, Yongwei

AU - Iwata, Takuya

AU - Nam, Kwangwoo

AU - Kimura, Tsuyoshi

AU - Wu, Pingli

AU - Nakamura, Naoko

AU - Hashimoto, Yoshihide

AU - Kishida, Akio

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Water absorption by decellularized dermis was investigated and compared with biopolymer and synthetic polymer hydrogels (glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogel, respectively). Porcine dermis was decellularized in an aqueous sodium dodecyl sulfate (SDS) solution. Histological evaluation revealed that the SDS-treated dermis has much larger gaps between collagen fibrils than non-treated dermis, and that water absorption depends on these gaps. Decellularized dermis has low water absorptivity and the absorption obeys Fick's second law. During absorption, the water diffusion rate decreases with time and occurs in two steps. The first is rapid absorption into the large gaps, followed by slow absorption by the collagen fiber layer. Because of the gaps, decellularized dermis can absorb more water than native dermis and shows different water absorption behavior to glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogels.

AB - Water absorption by decellularized dermis was investigated and compared with biopolymer and synthetic polymer hydrogels (glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogel, respectively). Porcine dermis was decellularized in an aqueous sodium dodecyl sulfate (SDS) solution. Histological evaluation revealed that the SDS-treated dermis has much larger gaps between collagen fibrils than non-treated dermis, and that water absorption depends on these gaps. Decellularized dermis has low water absorptivity and the absorption obeys Fick's second law. During absorption, the water diffusion rate decreases with time and occurs in two steps. The first is rapid absorption into the large gaps, followed by slow absorption by the collagen fiber layer. Because of the gaps, decellularized dermis can absorb more water than native dermis and shows different water absorption behavior to glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogels.

KW - Bioengineering

KW - Materials science

UR - http://www.scopus.com/inward/record.url?scp=85045197258&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045197258&partnerID=8YFLogxK

U2 - 10.1016/j.heliyon.2018.e00600

DO - 10.1016/j.heliyon.2018.e00600

M3 - Article

AN - SCOPUS:85045197258

VL - 4

JO - Heliyon

JF - Heliyon

SN - 2405-8440

IS - 4

M1 - e00600

ER -