Within-subject reproducibility of near-infrared spectroscopy signals in sensorimotor activation after 6 months

Hiroki Satou, Masashi Kiguchi, Atsushi Maki, Yutaka Fuchino, Akiko Obata, Takeshi Yoro, Hideaki Koizumi

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Near-infrared spectroscopy (NIRS) can measure the product of the optical path length and the concentration change in oxygenated hemoglobin (ΔC oxy), deoxygenated hemoglobin (ΔCdeoxy), and their sum (ΔCtotal) in the human cerebral cortex, and it has been used for noninvasive investigation of human brain functions. We evaluate the within-subject reproducibility of the NIRS signals by repeated measurement of the sensorimotor cortex in healthy adults taken over a period of about 6 months using near-infrared (NIR) topography. The maximum signal amplitudes and the location of activation centers are compared between two sessions for each subject. The signal amplitudes vary between sessions and no consistent tendency in the changes is found among subjects. However, the distance between the activation centers identified in two sessions is relatively small, within 20 mm on average across subjects, which is comparable to the smallest distance between measurement positions in the NIR topography (21 mm). Moreover, within-subject comparisons of signal time courses show high correlation coefficients (>0.8) between the two sessions. This result, demonstrating a high within-subject reproduc-ibility of the temporal information in NIRS signals, particularly contributes to the development of a new application of NIRS.

Original languageEnglish
Article number014021
JournalJournal of Biomedical Optics
Volume11
Issue number1
DOIs
Publication statusPublished - 2006 Jan 1
Externally publishedYes

Fingerprint

Near infrared spectroscopy
Chemical activation
infrared spectroscopy
activation
Hemoglobin
hemoglobin
Topography
topography
Hemoglobins
cerebral cortex
Infrared radiation
Distance measurement
time signals
cortexes
optical paths
correlation coefficients
brain
Brain
tendencies
products

Keywords

  • Finger tapping
  • Hemoglobin
  • Near-infrared spectroscopy
  • Reproducibility
  • Sensorimotor cortex

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

Cite this

Within-subject reproducibility of near-infrared spectroscopy signals in sensorimotor activation after 6 months. / Satou, Hiroki; Kiguchi, Masashi; Maki, Atsushi; Fuchino, Yutaka; Obata, Akiko; Yoro, Takeshi; Koizumi, Hideaki.

In: Journal of Biomedical Optics, Vol. 11, No. 1, 014021, 01.01.2006.

Research output: Contribution to journalArticle

Satou, Hiroki ; Kiguchi, Masashi ; Maki, Atsushi ; Fuchino, Yutaka ; Obata, Akiko ; Yoro, Takeshi ; Koizumi, Hideaki. / Within-subject reproducibility of near-infrared spectroscopy signals in sensorimotor activation after 6 months. In: Journal of Biomedical Optics. 2006 ; Vol. 11, No. 1.
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