濱崎 啓太

研究成果

年別の研究成果 1992 2000 2006 2018

• 72 Article
• 1 Letter
• 1 Review article

年別の研究成果

年別の研究成果

検索結果

• 2018

  Hydrophobic association of a side chains induces reversible helix folding in a dual aromatic ring tagged short peptide

  Tsuchie, R., Shimosato, M. & Hamasaki, K., 2018, In: Chemistry Letters. 47, 10, p. 1276-1278 3 p.

  研究成果: Article › 査読

  • Naphthalene 100%
  • Aromatic Structure 95%
  • Peptide 63%
  • Excimer Fluorescence 25%
  • Fluorescence Spectrum 16%
• 2015

  Nucleobase modified neamines with a lysine as a linker, their inhibition specificity for TAR-Tat derived from HIV-1

  Inoue, R., Watanabe, K., Katou, T., Ikezawa, Y. & Hamasaki, K., 2015 5月 1, In: Bioorganic and Medicinal Chemistry. 23, 9, p. 2139-2147 9 p.

  研究成果: Article › 査読

  • neamine 100%
  • Neamine 87%
  • Nucleobase 56%
  • Lysine 50%
  • HIV-1 45%
  7 被引用数 (Scopus)
• 2012

  A synthetic approach to aromatic aminoglycoside as a neamine mimic

  Inoue, R., Matsuda, S., Oda, Y., Ooyama, H., Yoshida, A., Hamasaki, K. & Yamanoi, T., 2012, In: Heterocycles. 84, 2, p. 1335-1343 9 p.

  研究成果: Article › 査読

  • neamine 100%
  • Neamine 87%
  • Aminoglycoside 69%
  • Aminoglycosides 57%
  • 2,4-diaminophenol 56%

• HostGuest-bridge Induces Irreversible Helix Folding in a Short Peptide

  Nakamura, Y., Nakazawa, K. & Hamasaki, K., 2012 9月 17, In: Chemistry Letters. 41, 9, p. 908-909 2 p.

  研究成果: Article › 査読

  • Peptide 100%

• Host-guest-bridge induces irreversible helix folding in a short peptide

  Nakamura, Y., Nakazawa, K. & Hamasaki, K., 2012 9月 5, In: Chemistry Letters. 41, p. 908-909

  研究成果: Article › 査読
• 2010

  6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-α-D-gluco-dec-5-ulopyranosyl 2,3,4,6-tetra-O-benzyl-α-D-glucopyranoside

  Yamanoi, T., Inoue, R., Oda, Y. & Hamasaki, K., 2010, In: MolBank. 2010, 2, p. 1-4 4 p.

  研究成果: Article › 査読

  • benzyl glucopyranoside 100%
  • D-Glucopyranose 71%
  • Methylene Chloride 61%
  • Triflate 46%
  • bismuth 44%
  1 被引用数 (Scopus)

• Cyclodextrin peptide hybrids as drug responsive flexible nano-materials

  Amano, H., Kobayashi, A., Yoshida, N. & Hamasaki, K., 2010 12月 17, In: 2010 international chemical congress of pacific basn societies. 2010, p. 101-101

  研究成果: Article › 査読

• Nucleobase modified heterocycles as a potential inhibitor for HIV TAR-Tat

  Hamasaki, K., Arai, R., Itozawa, M., kimura, T., Takahashi, K. & Uchida, Y., 2010 12月 20, In: 2010 International chemical congress of pacific basin societies. 2010, p. 147-147

  研究成果: Article › 査読
• 2009

  Formation of O-glycosidic lincages from 1-hydroxy sugers by Bismuth(III) triflate-catalyzed dehydrative glycosidation

  Yamanoi, T., Inoue, R., Matsuda, S., Iwao, K., Oda, Y., Yashida, A. & Hamasaki, K., 2009 8月 25, In: Heterocycles. 77, p. 445-460

  研究成果: Article › 査読

• Formation of O-glycosidic linkages from 1-hydroxy sugars by bismuth(III) triflate-catalyzed dehydrative glycosidation

  Yamanoi, T., Inoue, R., Matsuda, S., Iwao, K., Oda, Y., Yoshida, A. & Hamasaki, K., 2009 1月 1, In: Heterocycles. 77, 1, p. 445-460 16 p.

  研究成果: Article › 査読

  • Sugars 100%
  • Triflate 84%
  • Methylene Chloride 55%
  • Dichloromethane 35%
  • Temperature 29%
  12 被引用数 (Scopus)
• 2008

  Bismuth(III) triflate-catalyzed dehydrative glycosidation using 1-hydroxy sugars

  Yamanoi, T., Inoue, R., Matsuda, S. & Hamasaki, K., 2008 1月, In: Letters in Organic Chemistry. 5, 1, p. 30-33 4 p.

  研究成果: Article › 査読

  • Sugars 100%
  • Glycosides 82%
  • Methylene Chloride 46%
  • Primary Alcohol 37%
  • Triflate 35%
  8 被引用数 (Scopus)
• 2007

  Fluorous Lewis Acid-catalyzed Glycosidations

  Yamanoi, T., Inoue, R., Oda, Y., Yoshida, A. & Hamasaki, K., 2007 7月 30, In: The 2nd International symposium on fluorous technologies. p. 152-152

  研究成果: Article › 査読

• Modified neamines and neamine mimics, their synthesis and binding specificity for HIV TAR RNA

  Matsumoto, H., Mizuno, M., Katou, T., YasunoriIkezawa, Y., Yajima, S., Shionoya, H., Akagi, T. & Hamasaki, K., 2007 12月 3, In: The 4th Takeda foundation symposium on Pharmasciences, On the frontiers of chemical biology. 4, p. 106-106

  研究成果: Article › 査読

• Nucleobase modified neamines, their synthesis and binding specificity for HIV TAR RNA.

  Watanabe, K., Katou, T., Ikezawa, Y., Yajima, S., Shionoya, H., Akagi, T. & Hamasaki, K., 2007, In: Nucleic acids symposium series (2004). 51, p. 209-210 2 p.

  研究成果: Article › 査読

  • neamine 100%
  • RNA 36%
  • HIV 35%
  • Cytosine 15%
  • Guanine 15%
  4 被引用数 (Scopus)

• Nucleobase modified neamines, thier synthesis and binding specificity for HIV TAR RNA

  Watanabe, K., Katou, T., YasunoriIkezawa, Y., Yajima, S., Shionoya, H., Akagi, T. & Hamasaki, K., 2007 11月 21, In: 5th International synposium on nucleic acids chemistry. 51, p. 209-210

  研究成果: Article › 査読

• Synthesis of non-reducing disaccharides by the bismuth(III) triflate-catalyzed glycosidation

  Inoue, R., Sho, M., Yoshida, A., yamanoi, T. & Hamasaki, K., 2007 10月 7, In: Glycoconjugate Jornal. 24, p. 339-339

  研究成果: Article › 査読
• 2006

  Neamine derivatives having a nucleobase with a lysine or an arginine as a linker, their synthesis and evaluation as a potential inhibitor for HIV TAR-Tat

  Yajima, S., Shionoya, H., Akagi, T. & Hamasaki, K., 2006 1月 1, In: Bioorganic & Medicinal Chemistry. 14, p. 2799-2809

  研究成果: Article › 査読

• Neamine derivatives having a nucleobase with a lysine or an arginine as a linker, their synthesis and evaluation as potential inhibitors for HIV TAR-Tat

  Yajima, S., Shionoya, H., Akagi, T. & Hamasaki, K., 2006 4月 15, In: Bioorganic and Medicinal Chemistry. 14, 8, p. 2799-2809 11 p.

  研究成果: Article › 査読

  • neamine 100%
  • Neamine 87%
  • Nucleobase 56%
  • Arginine 52%
  • Lysine 50%
  19 被引用数 (Scopus)

• Synthesis of aminoglycoside derivatives on a Cbz-type heavy fluorous tag

  Mizuno, M., Matsumoto, H., Goto, K. & Hamasaki, K., 2006 12月 11, In: Tetrahedron Letters. 47, 50, p. 8831-8835 5 p.

  研究成果: Article › 査読

  • Aminoglycoside 100%
  • Aminoglycosides 82%
  • Alcohols 56%
  • Disaccharides 49%
  • Alcohol 45%
  19 被引用数 (Scopus)

• Synthesis of aminoglycoside derivatives on a Cbz-type of heavy fluorous tag

  Mizuno, M., Matsumoto, H., Goto, K. & Hamasaki, K., 2006 11月 1, In: Tetrahedron Lettes. 47, p. 8831-8835

  研究成果: Article › 査読

• Synthesis of trehalose mimics by bismuth(III) triflate or bis(trifluoromethane)sulfonimide-catalyzed 1-C-methyl-d-hexopyranosylation

  Yamanoi, T., Inoue, R., Matsuda, S., Katsuraya, K. & Hamasaki, K., 2006 11月 6, In: Tetrahedron Asymmetry. 17, 20, p. 2914-2918 5 p.

  研究成果: Article › 査読

  • Disaccharides 100%
  • Trehalose 96%
  • Bismuth 70%
  • Disaccharide 54%
  • Triflate 53%
  22 被引用数 (Scopus)

• Synthesis of trehalose mimics by bismuth(III) triflate or bis (trifluoromethane) sulfonimide-catalyzed 1-C-methyl-D-hexopyranosylation.

  Takashi, Y., Ryo, I., Sho, M., Kaname, K., Keita, H. & Hamasaki, K., 2006 1月 1, In: Tetrahedron:Asymmetry. p. 2914-2918

  研究成果: Article › 査読

  22 被引用数 (Scopus)

• The Brensted acid catalzyed O-glycosilation of 1-C-alkyl-D-glucopylanose

  Yamanoi, T., Matsuda, S., Yamazaki, I., Inoue, R., Hamasaki, K. & Watanabe, M., 2006 1月 1, In: Heterocycles. 68, p. 673-677

  研究成果: Article › 査読

• The brθnsted acid-catalyzed O-glycosidation of 1-C-alkyl-D-glucopyranose derivatives

  Yamanoi, T., Matsuda, S., Yamazaki, I., Inoue, R., Hamasaki, K. & Watanabe, M., 2006 4月 1, In: Heterocycles. 68, 4, p. 673-677 5 p.

  研究成果: Article › 査読

  • trifluoromethanesulfonic acid 100%
  • Acids 39%
  • Alcohols 39%
  • Alcohol 31%
  • Reaction Yield 21%
  11 被引用数 (Scopus)
• 2005

  Amino disaccharides having an alpha-(1-->4) or a beta-(1-->4) linkage, their synthesis and evaluation as a potential inhibitor for HIV-1 TAR-Tat.

  Iguchi, T., Ishikawa, H., Matumoto, H., Mizuno, M., Goto, K. & Hamasaki, K., 2005, In: Nucleic acids symposium series (2004). 49, p. 169-170 2 p.

  研究成果: Article › 査読

  Open Access

  • Disaccharides 100%
  • Glycosides 92%
  • HIV-1 66%
  • Anti-Bacterial Agents 50%
  2 被引用数 (Scopus)

• Amino disaccharides having an α-(1->4) or β-(1->4) linkage, their synthesis and evaluation as a potential inhibitor for HIV-1 TAR-tat.

  Takashi, I., Hirofumi, I., Hiroharu, M., Mamoru, M., Kohtaro, G., Keita, H. & Hamasaki, K., 2005 1月 1, In: Nucleic acids symposium series. p. 169-170

  研究成果: Article › 査読

• Neamine derivatives and mimics, Their synthsis and evaluation as a potential inhibitor for HIV TAR-Tat

  Hamasaki, K., Matsumoto, H., Yajima, S., Shionoya, H., Akagi, T. & Iguchi, T., 2005 12月 19, In: 2005 International chemical congress of pacific basin societies. 2005, p. 102-102

  研究成果: Article › 査読

• Preparation of peptide-bonded cyclodextrin derivative capable of forming host-guest bridge as shape memory element

  Hamasaki, K., 2005 1月 1, In: Jpn. Kokai Tokkyo Koho. p. 13

  研究成果: Article › 査読

• Techniques of SNP genotyping and remote sensing applied for elucidation of the contribution of polygene and environmental factors to inter-individual variation in skin pigmentation phenotype

  Anno, S., Kudo, S., Hamasaki, K., Matsumura, K., Yamamoto, T. & Ogata, K., 2005 7月, In: Journal of Physiological Anthropology and Applied Human Science. 24, 4, p. 483-486 4 p.

  研究成果 › 査読

  • Genotyping Techniques 100%
  • Skin Pigmentation 74%
  • Computational methods 65%
  • Genomics 64%
  • Remote sensing 64%
  1 被引用数 (Scopus)
• 2003

  Supramolecular chemistry of cyclodextrin-peptide hybrids: Azobenzen-tagged peptides

  Ueno, A., Shimizu, T., Mihara, HI., Hamasaki, K. & Pichumani, K., 2003 4月 1, In: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 44, p. 1-4

  研究成果: Article › 査読
• 2002

  Double naphthalene-tagged cyclodextrin-peptide capable of exhibiting guest-induced naphthalene excimer fluorescence

  Yana, D., Shimizu, T., Hamasaki, K., Mihara, H. & Ueno, A., 2002 1月 9, In: Macromolecular Rapid Communications. 23, 1, p. 11-15 5 p.

  研究成果: Article › 査読

  • Cyclodextrins 100%
  • Excimer Fluorescence 83%
  • Naphthalene 83%
  • Peptides 78%
  • Fluorescence 68%
  19 被引用数 (Scopus)

• Fluorescent protein and drug screening method

  Hamasaki, K., 2002 1月 1, In: Jpn. Kokai Tokkyo Koho. p. 7

  研究成果: Article › 査読

• Supramolecular chemistry of cyclodextrin-peptide hybrids: Azobenzene-tagged peptides

  Ueno, A., Shimizu, T., Mihara, H., Hamasaki, K. & Pitchumani, K., 2002, In: Journal of Inclusion Phenomena. 44, 1-4, p. 49-52 4 p.

  研究成果: Article › 査読

  • azobenzene 100%
  • Cyclodextrins 78%
  • cyclodextrins 76%
  • Supramolecular Chemistry 70%
  • peptides 63%
  5 被引用数 (Scopus)
• 2001

  Aminoglycoside antibiotics, neamine and its derivatives as potent inhibitors for the RNA-protein interactions derived from HIV-1 activators

  Hamasaki, K. & Ueno, A., 2001 2月 26, In: Bioorganic and Medicinal Chemistry Letters. 11, 4, p. 591-594 4 p.

  研究成果: Article › 査読

  • neamine 100%
  • Neamine 87%
  • Aminoglycoside Antibiotic Agent 72%
  • Aminoglycosides 57%
  • Arginine 52%
  51 被引用数 (Scopus)

• Construction of peptides with nucleobase amino acids: Design and synthesis of the nucleobase-conjugated peptides derived from HIV-1 rev and their binding properties to HIV-1 RRE RNA

  Takahashi, T., Hamasaki, K., Ueno, A. & Mihara, H., 2001 4月, In: Bioorganic and Medicinal Chemistry. 9, 4, p. 991-1000 10 p.

  研究成果: Article › 査読

  • Nucleobase 100%
  • HIV-1 80%
  • Amino Acids 64%
  • RNA 63%
  • Peptides 58%
  23 被引用数 (Scopus)

• Fluorescent cyclodextrin immobilized on a cellulose membrane as a chemosensor system for detecting molecules

  Tanabe, T., Touma, K., Hamasaki, K. & Ueno, A., 2001 4月 15, In: Analytical Chemistry. 73, 8, p. 1877-1880 4 p.

  研究成果: Article › 査読

  • Cyclodextrins 100%
  • Cellulose 65%
  • Molecules 58%
  • Cyclodextrin 57%
  • Membranes 50%
  24 被引用数 (Scopus)

• HIV Rev peptides conjugated with peptide nucleic acids and their efficient binding to RRE RNA

  Kumagai, I., Takahashi, T., Hamasaki, K., Ueno, A. & Mihara, H., 2001 5月 7, In: Bioorganic and Medicinal Chemistry Letters. 11, 9, p. 1169-1172 4 p.

  研究成果: Article › 査読

  • Rev peptide 100%
  • Peptide Nucleic Acids 73%
  • env Genes 69%
  • Peptide Nucleic Acid 62%
  • RNA 34%
  13 被引用数 (Scopus)

• Immobilized fluorescent cyclodextrin on a cellulose membrane as a chemosensor for molecule detection

  Tanabe, T., Touma, K., Hamasaki, K. & Ueno, A., 2001 7月 1, In: Analytical Chemistry. 73, 13, p. 3126-3130 5 p.

  研究成果: Article › 査読

  • Cyclodextrins 100%
  • Cellulose 65%
  • Molecules 58%
  • Cyclodextrin 57%
  • Membranes 50%
  39 被引用数 (Scopus)

• Remarkable stabilization of the α-helix structure by an intramolecular host-guest bridge in a cyclodextrin-peptide hybrid

  Hamasaki, K., Suzuki, R., Mihara, H. & Ueno, A., 2001 2月 28, In: Macromolecular Rapid Communications. 22, 4, p. 262-265 4 p.

  研究成果: Article › 査読

  • Cyclodextrins 100%
  • Peptides 78%
  • Cholic Acid 78%
  • Stabilization 50%
  • Acids 15%
  1 被引用数 (Scopus)
• 2000

  A high-throughput screening utilization intramolecular fluorescence resonance energy transfer for the discovery of the molecules that bind HIV-1 TAR RNA specifically

  Matsumoto, C., Hamasaki, K., Mihara, H. & Ueno, A., 2000 8月 21, In: Bioorganic and Medicinal Chemistry Letters. 10, 16, p. 1857-1861 5 p.

  研究成果: Article › 査読

  • Fluorescence Resonance Energy Transfer 100%
  • High Throughput Screening 80%
  • HIV-1 65%
  • tetramethylrhodamine 63%
  • Tetramethylrhodamine 55%
  54 被引用数 (Scopus)

• A High-throughput screening utilizing intramolcular fluorescence resonance energy transfer for the discovery of the molecules that bind HIV-1 TAR RNA specifically

  Matsumoto, C., Hamasaki, K., Mihara, H. & Ueno, A., 2000 1月 1, In: Bioorganic and Medicinal Chemistry Letters. p. 1857-1861

  研究成果: Article › 査読

• An aminoglycoside antibiotic, neamine, and its aromatic ring substituted derivatives as potential inhibitors for HIV-1 RRE Rev

  Hamasaki, K., Woo, M-C. & Ueno, A., 2000 1月 2, In: Tetrahedron Letters. p. 8327-8332

  研究成果: Article › 査読

  24 被引用数 (Scopus)

• An aminoglycoside antibiotic, neamine, and its aromatic ring-substituted derivatives as potential inhibitors for HIV-1 RRE-Rev

  Hamasaki, K., Woo, M. C. & Ueno, A., 2000 10月 21, In: Tetrahedron Letters. 41, 43, p. 8327-8332 6 p.

  研究成果: Article › 査読

  • neamine 100%
  • Neamine 87%
  • Aminoglycoside Antibiotic Agent 72%
  • Aminoglycosides 57%
  • HIV-1 45%
  24 被引用数 (Scopus)

• Association and guest-induced dissociation of a novel α-helix peptide bearing pyrene and γ-cyclodextrin in the side chains

  Hossain, M. A., Hamasaki, K., Mihara, H. & Ueno, A., 2000, In: Chemistry Letters. 3, p. 252-253 2 p.

  研究成果: Article › 査読

  • Hyodeoxycholic Acid 100%
  • Excimer 63%
  • Pyrene 57%
  • Dissociation 42%
  • Monomer 34%
  13 被引用数 (Scopus)

• Association of α-helix peptides that have γ-cyclodextrin and pyrene units in their side chain, and induction of dissociation of the association dimer by external stimulant molecules

  Hossain, M. A., Matsumura, S., Kanai, T., Hamasaki, K., Mihara, H. & Ueno, A., 2000 7月, In: Journal of the Chemical Society. Perkin Transactions 2. 7, p. 1527-1533 7 p.

  研究成果: Article › 査読

  • Analeptic Agent 100%
  • Pyrene 76%
  • Excimer 56%
  • Dissociation 56%
  • Peptide 45%
  33 被引用数 (Scopus)

• Construction of HIV Rev peptides containing peptide nucleic acid that bind HIV RRE IIB RNA

  Kumagai, I., Takahashi, T., Hamasaki, K., Ueno, A. & Mihara, H., 2000 2月 21, In: Bioorganic and Medicinal Chemistry Letters. 10, 4, p. 377-379 3 p.

  研究成果: Article › 査読

  • Rev peptide 100%
  • Peptide Nucleic Acids 73%
  • env Genes 69%
  • Peptide Nucleic Acid 62%
  • RNA 34%
  11 被引用数 (Scopus)

• Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups

  Tsutsumi, H., Hamasaki, K., Mihara, H. & Ueno, A., 2000 4月, In: Bioorganic and Medicinal Chemistry Letters. 10, 8, p. 741-743 3 p.

  研究成果: Article › 査読

  • Cyclodextrins 100%
  • Peptides 46%
  • Hydrolysis 45%
  • Ester 44%
  • Peptide 42%
  19 被引用数 (Scopus)

• Cyclodextrin-peptide hybrids (CD-peptide)1, Synthesis and properties of alph helix peptide bearing gamma cyclodextrin and pyrene in their side chains

  Hossain, M. A., Matsumura, S., Toyoda, T., Hamasaki, K., Mihara, H. & Ueno, A., 2000 5月 1, In: 10th International Cyclodextrin Symposium.

  研究成果: Article › 査読

• Cyclodextrin-peptide hybrids (CD-peptide)2, Photoresponsive alph helix peptides bearing an azobenzine and a beta- or gamma cyclodextrin in their side chains

  Shimizu, T., Hamasaki, K. & Ueno, A., 2000 5月 1, In: 10th International Cyclodextrin Symposium.

  研究成果: Article › 査読

• Cyclodextrin-peptide hybrids for molecule sensing and artificial enzymes

  Ueno, A., Matsumura, S., Hossain, M. A., Tsutsumi, H., Toyoda, T., Shimizu, T., Suzuki, R., Kanai, T., Hamasaki, K. & Mihara, H., 2000 5月 1, In: 10th International Cyclodextrin Symposium.

  研究成果: Article › 査読