北川 理

研究成果

年別の研究成果 1985 2021

• 4646 被引用数
• 42 h-index
• 163 Article
• 3 Review article
• 2 Comment/debate

年別の研究成果

年別の研究成果

検索結果

• 2021

  Chiral Pd-Catalyzed Enantioselective Syntheses of Various N-C Axially Chiral Compounds and Their Synthetic Applications

  Kitagawa, O., 2021 2 2, In: Accounts of Chemical Research. 54, 3, p. 719-730 12 p.

  研究成果: Article › 査読

  • Indoles
  • 4-hydroxyquinazoline
  • Lactams
  • Derivatives
  • Allylation

• Thionation of Optically Pure N-C Axially Chiral Quinazolin-4-one Derivatives with Lawesson's Reagent

  Niijima, E., Imai, T., Suzuki, H., Fujimoto, Y. & Kitagawa, O., 2021 1 1, In: Journal of Organic Chemistry. 86, 1, p. 709-715 7 p.

  研究成果: Article › 査読

  • 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide
  • 4-hydroxyquinazoline
  • Thiones
  • Derivatives
  • Quinazolines
• 2020

  Relayed Proton Brake in N-Pyridyl-2-iso-propylaniline Derivative: Two Brakes with One Proton

  Furukawa, G., Shirai, T., Homma, Y., Caytan, E., Vanthuyne, N., Farran, D., Roussel, C. & Kitagawa, O., 2020 4 3, In: Journal of Organic Chemistry. 85, 7, p. 5109-5113 5 p.

  研究成果: Article › 査読

  • Protonation
  • methanesulfonic acid
  • pyridine
  • Deceleration
  • Atoms
  2 被引用数 (Scopus)
• 2019

  Catalytic Enantioselective Synthesis of N-C Axially Chiral Sulfonamides through Chiral Palladium-Catalyzed N-Allylation

  Kikuchi, Y., Nakamura, C., Matsuoka, M., Asami, R. & Kitagawa, O., 2019 6 21, In: Journal of Organic Chemistry. 84, 12, p. 8112-8120 9 p.

  研究成果: Article › 査読

  • Allylation
  • Palladium
  • Sulfonamides
  • allyl acetate
  • Catalysts
  8 被引用数 (Scopus)

• Chirality-dependent halogen bonds in axially chiral quinazolin-4-one derivatives bearing: Ortho -halophenyl groups

  Imai, T., Niijima, E., Terada, S., Wzorek, A., Soloshonok, V. A., Hori, A. & Kitagawa, O., 2019, In: CrystEngComm. 21, 22, p. 3385-3389 5 p.

  研究成果: Article › 査読

  • 4-hydroxyquinazoline
  • Chirality
  • Halogens
  • halogens
  • chirality
  1 被引用数 (Scopus)

• N-C Axially Chiral Compounds with an ortho-Fluoro Substituent and Steric Discrimination between Hydrogen and Fluorine Atoms Based on a Diastereoselective Model Reaction

  Iida, A., Matsuoka, M., Hasegawa, H., Vanthuyne, N., Farran, D., Roussel, C. & Kitagawa, O., 2019 3 15, In: Journal of Organic Chemistry. 84, 6, p. 3169-3175 7 p.

  研究成果: Article › 査読

  • Fluorine
  • 4-hydroxyquinazoline
  • Hydrogen
  • Atoms
  • Allylation
  4 被引用数 (Scopus)

• The self-disproportionation of enantiomers (SDE) of α-amino acid derivatives: facets of steric and electronic properties

  Hosaka, T., Imai, T., Wzorek, A., Marcinkowska, M., Kolbus, A., Kitagawa, O., Soloshonok, V. A. & Klika, K. D., 2019 2 7, In: Amino Acids. 51, 2, p. 283-294 12 p.

  研究成果: Article › 査読

  • Electronic properties
  • Esters
  • Density Functional Theory
  • Derivatives
  • Chemical Industry
  5 被引用数 (Scopus)
• 2018

  N−C Axially Chiral Anilines: Electronic Effect on Barrier to Rotation and A Remote Proton Brake

  Iwasaki, Y., Morisawa, R., Yokojima, S., Hasegawa, H., Roussel, C., Vanthuyne, N., Caytan, E. & Kitagawa, O., 2018 3 20, In: Chemistry - A European Journal. 24, 17, p. 4453-4458 6 p.

  研究成果: Article › 査読

  • Aniline Compounds
  • Aniline
  • Protons
  • Electrons
  • methylaniline
  11 被引用数 (Scopus)

• α-Alkylation of N-C Axially Chiral Quinazolinone Derivatives Bearing Various ortho -Substituted Phenyl Groups: Relation between Diastereoselectivity and the ortho -Substituent

  Matsuoka, M., Iida, A. & Kitagawa, O., 2018 5 29, In: Synlett. 29, 16, p. 2126-2130 5 p.

  研究成果: Article › 査読

  • Quinazolinones
  • Chirality
  • Alkylation
  • Derivatives
  • Temperature
  2 被引用数 (Scopus)
• 2017

  Diastereoselective α-Alkylation of Metallo Enamines Generated from N-C Axially Chiral Mebroqualone Derivatives

  Matsuoka, M., Goto, M., Wzorek, A., Soloshonok, V. A. & Kitagawa, O., 2017 5 19, In: Organic Letters. 19, 10, p. 2650-2653 4 p.

  研究成果: Article › 査読

  • alkylation
  • Chirality
  • Alkylation
  • halides
  • chirality
  11 被引用数 (Scopus)

• Possible Case of Halogen Bond-Driven Self-Disproportionation of Enantiomers (SDE) via Achiral Chromatography

  Terada, S., Hirai, M., Honzawa, A., Kitagawa, O., Kamizela, A., Wzorek, A. & Soloshonok, V. A., 2017 10 17, In: Chemistry - A European Journal. 23, 58, p. 14631-14638 8 p.

  研究成果: Article › 査読

  • Enantiomers
  • Halogens
  • Chromatography
  • Chirality
  • Hydrogen bonds
  10 被引用数 (Scopus)

• Specific reactivity of 2,4,6-tri-tert-butylanilide anions and its application to benzylation reagent

  Yamada, T., Tsukagoshi, S. & Kitagawa, O., 2017 1 25, In: Tetrahedron Letters. 58, 4, p. 317-320 4 p.

  研究成果: Article › 査読

  • Anilides
  • Imidoesters
  • Anions
  • Alkylation
  • benzyl bromide
  1 被引用数 (Scopus)
• 2016

  Catalytic Enantioselective Synthesis of N-C Axially Chiral Mebroqualone and Its Derivatives through Reductive Asymmetric Desymmetrization

  Hirai, M., Terada, S., Yoshida, H., Ebine, K., Hirata, T. & Kitagawa, O., 2016 11 4, In: Organic Letters. 18, 21, p. 5700-5703 4 p.

  研究成果: Article › 査読

  • palladium(II) acetate
  • 4-hydroxyquinazoline
  • Quinazolinones
  • Sodium Borohydride
  • catalysts
  27 被引用数 (Scopus)

• Catalytic Enantioselective Synthesis of N-C Axially Chiral Phenanthridin-6-one Derivatives

  Hirata, T., Takahashi, I., Suzuki, Y., Yoshida, H., Hasegawa, H. & Kitagawa, O., 2016 1 4, In: Journal of Organic Chemistry. 81, 1, p. 318-323 6 p.

  研究成果: Article › 査読

  • palladium(II) acetate
  • Amination
  • Atoms
  • Nitrogen
  • Derivatives
  24 被引用数 (Scopus)

• Chiral additive induced self-disproportionation of enantiomers under MPLC conditions: Preparation of enantiomerically pure samples of 1-(aryl)ethylamines from racemates

  Goto, M., Tateishi, K., Ebine, K., Soloshonok, V. A., Roussel, C. & Kitagawa, O., 2016 5 1, In: Tetrahedron Asymmetry. 27, 7-8, p. 317-321 5 p.

  研究成果: Article › 査読

  • Ethylamines
  • Enantiomers
  • enantiomers
  • preparation
  • Liquid chromatography
  11 被引用数 (Scopus)

• Enantioselective synthesis of N–C axially chiral indoles through chiral palladium-catalyzed 5-endo-hydroaminocyclization

  Morimoto, Y., Shimizu, S., Mokuya, A., Ototake, N., Saito, A. & Kitagawa, O., 2016, In: Tetrahedron. 72, 34, p. 5221-5229 9 p.

  研究成果: Article › 査読

  • Aniline Compounds
  • Indoles
  • Chirality
  • Palladium
  • Carrier concentration
  17 被引用数 (Scopus)
• 2015

  A comprehensive examination of the self-disproportionation of enantiomers (SDE) of chiral amides via achiral, laboratory-routine, gravity-driven column chromatography

  Suzuki, Y., Han, J., Kitagawa, O., Aceña, J. L., Klika, K. D. & Soloshonok, V. A., 2015, In: RSC Advances. 5, 4, p. 2988-2993 6 p.

  研究成果: Article › 査読

  • Enantiomers
  • Column chromatography
  • Amides
  • Gravitation
  • Chromatography
  40 被引用数 (Scopus)

• Relationship between rotational barriers and structures in N-C axially chiral 3,4-dihydroquinolin-2-one and 3,4-dihydrobenzoquinolin-2-one

  Suzuki, Y., Takahashi, I., Dobashi, Y., Hasegawa, H., Roussel, C. & Kitagawa, O., 2015 1 1, In: Tetrahedron Letters. 56, 1, p. 132-135 4 p.

  研究成果: Article › 査読

  • Ground state
  • Crystal structure
  • Nuclear magnetic resonance
  • Proton Magnetic Resonance Spectroscopy
  • X rays
  8 被引用数 (Scopus)

• The synthesis of optically active N-C axially chiral tetrahydroquinoline and its response to an acid-accelerated molecular rotor

  Suzuki, Y., Kageyama, M., Morisawa, R., Dobashi, Y., Hasegawa, H., Yokojima, S. & Kitagawa, O., 2015 7 18, In: Chemical Communications. 51, 56, p. 11229-11232 4 p.

  研究成果: Article › 査読

  • 1,2,3,4-tetrahydroquinoline
  • quinoline
  • Methane
  • Sulfonic Acids
  • Acids
  10 被引用数 (Scopus)
• 2013

  Chiral initiator-induces self-disproportionation of enantiomers via achiral chromatography: Application to enantiomer separation of racemate

  Tateishi, K., Tsukagoshi, S., Nakamura, T., Watanabe, S., Soloshonok, V. A. & Kitagawa, O., 2013 9 18, In: Tetrahedron Letters. 54, 38, p. 5220-5223 4 p.

  研究成果: Article › 査読

  • Chromatography
  18 被引用数 (Scopus)

• Rotational isomerism in 2,4,6-tri-tert-butylanilides

  Ototake, N., Takahashi, I., Tsukagoshi, S., Maeda, T. & Kitagawa, O., 2013 1 21, In: Tetrahedron. 69, 3, p. 1013-1016 4 p.

  研究成果: Article › 査読

  • Anilides
  • Isomerism
  • Hydrogen
  • Heating
  • Isomerization
  1 被引用数 (Scopus)

• Unique structural properties of 2,4,6-tri-tert-butylanilide: Isomerization and switching between separable amide rotamers through the reaction of anilide enolates

  Tsukagoshi, S., Ototake, N., Ohnishi, Y., Shimizu, M. & Kitagawa, O., 2013 5 17, In: Chemistry - A European Journal. 19, 21, p. 6845-6850 6 p.

  研究成果: Article › 査読

  • Anilides
  • Amides
  • Isomerization
  • Structural properties
  • Protonation
  4 被引用数 (Scopus)
• 2012

  Catalytic enantioselective synthesis of atropisomeric 2-aryl-4-quinolinone derivatives with an N-C chiral axis

  Takahashi, I., Morita, F., Kusagaya, S., Fukaya, H. & Kitagawa, O., 2012 12 15, In: Tetrahedron: Asymmetry. 23, p. 1657-1662

  研究成果: Article › 査読

  30 被引用数 (Scopus)

• Catalytic enantioselective synthesis of atropisomeric 2-aryl-4-quinolinone derivatives with an N-C chiral axis

  Takahashi, I., Morita, F., Kusagaya, S., Fukaya, H. & Kitagawa, O., 2012 12 31, In: Tetrahedron Asymmetry. 23, 24, p. 1657-1662 6 p.

  研究成果: Article › 査読

  • Amination
  • 4-Quinolones
  • aniline
  • ketones
  • Enantioselectivity
  30 被引用数 (Scopus)

• Catalytic Enantioselective Synthesis of Atropisomeric 4-Quinolinones with an N-C Chiral axis

  Takahashi, I., Fumika, F., Morita, M., Izumi, S. & Kitagawa, O., 2012 10 30, In: Default journal.

  研究成果: Article › 査読

• Enantiomer Enrichment of Non-racemic Chiral Amine Derivatives through Achiral Chromatography

  Tateishi, K., Nakamura, T., Tsukagoshi, S. & Kitagawa, O., 2012 5 17, In: Default journal.

  研究成果: Article › 査読

• Reversible Interconversion between Rotational Isomers of 2,4,6-Tri-tert-butylanilides

  Tsukagoshi, S., Yusuke, Y., Ohnishi, O. & Kitagawa, O., 2012 10 30, In: Default journal.

  研究成果: Article › 査読

• Self-disproportionation of enantiomers of non-racemic chiral amine derivatives through achiral chromatography

  Nakamura, T., Tateishi, K., Tsukagoshi, S., Hashimoto, S., Watanabe, S., Soloshonok, V. A., Aceña, J. L. & Kitagawa, O., 2012 5 27, In: Tetrahedron. 68, 21, p. 4013-4017 5 p.

  研究成果: Article › 査読

  • Acetamides
  • acetamide
  • Chromatography
  • Amines
  • Derivatives
  46 被引用数 (Scopus)

• Self-disproportionation of enantiomers via achiral chromatography: A warning and an extra dimension in optical purifications

  Soloshonok, V. A., Roussel, C., Kitagawa, O. & Sorochinskya, A. E., 2012 5 15, In: Chemical Society Reviews. 41, 11, p. 4180-4188 9 p.

  研究成果: Article › 査読

  • Chromatography
  • Purification
  • Chirality
  • Organic compounds
  • Functional groups
  113 被引用数 (Scopus)

• Self-disproportionation of enantiomers via achiral chromatography: a warning and an extra dimension in optical purifications

  Soloshono, V., Roussel, C., Kitagawa, O., Alex, A. & Sorochinsky, E., 2012 6 2, In: Chem. Soc. Rev.. 41, p. 4180-4188

  研究成果: Article › 査読

  113 被引用数 (Scopus)

• Studies on rotational barriers of N-C axially chiral compounds: Increase in the rotational barrier by aromatization

  Suzumura, N., Kageyama, M., Kamimura, D., Inagaki, T., Dobashi, Y., Hasegawa, H., Fukaya, H. & Kitagawa, O., 2012 8 15, In: Tetrahedron Letters. 53, 33, p. 4332-4336 5 p.

  研究成果: Article › 査読

  • Density Functional Theory
  • Aromatization
  • Discrete Fourier transforms
  • Nitrogen
  14 被引用数 (Scopus)

• Studies on rotational barriers of N-C axially chiral compounds: increase in the rotational barrier by aromatization

  Suzumura, N., Kageyama, M., Kamimura, D., Inagak, T., Dobashi, Y., Hasegawa, H., Fukaya, H. & Kitagawa, O., 2012 8 1, In: Tetrahedron Lett. 53, p. 4332-4336

  研究成果: Article › 査読

  14 被引用数 (Scopus)

• Study on Rotational Barrier of N-C Axially Chiral Compounds: Remarkable Increase in the ROtational Barrier by Aromatization

  Suzumura, N., Kageyama, M., Dobashi, Y. & Kitagawa, O., 2012 5 17, In: Default journal.

  研究成果: Article › 査読
• 2011

  Catalytic enantioselective synthesis of novel atropisomeric compounds having an N-C chiral axis and their application to asymmetric reaction

  Takahashi, M. & Kitagawa, O., 2011 9, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 69, 9, p. 985-993 9 p.

  研究成果: Article › 査読

  • Anilides
  • Lactams
  • palladium(II) acetate
  • palladium chloride
  • Amination
  13 被引用数 (Scopus)

• Intramolecular Diels-Alder reaction of N-allyl 2-furoyl amides: Effect of steric strain and amide rotational isomerism

  Nakamura, M., Takahashi, I., Yamada, S., Dobashi, Y. & Kitagawa, O., 2011 1 5, In: Tetrahedron Letters. 52, 1, p. 53-55 3 p.

  研究成果: Article › 査読

  • Cyclization
  • Cycloaddition Reaction
  • Isomerism
  • Amides
  • Discrete Fourier transforms
  20 被引用数 (Scopus)

• Intramolecular Diels-Alder Reaction of N-Allyl 2-Furoyl Amides: Effect of Steric Strain and Amide Rotational Isomerism

  Nakamura, M., Takahashi, I., Yamada, S., Dobashi, Y. & Kitagawa, O., 2011 1 1, In: Tetrahedron Lett. 52, p. 53-55

  研究成果: Article › 査読

  20 被引用数 (Scopus)

• Notable structural property of 2,4,6-Tri- tert -butylanilide enolates: Interconversion between the rotamers and their reactivity

  Ohnishi, Y., Sakai, M., Nakao, S. & Kitagawa, O., 2011 6 3, In: Organic Letters. 13, 11, p. 2840-2843 4 p.

  研究成果: Article › 査読

  • Anilides
  • Structural properties
  • Lithium
  • reactivity
  • Protonation
  8 被引用数 (Scopus)

• Notable Structural Property of 2,4,6-Tri-tert-butylanilide Enolates: Interconversion between the Rotamers and Their Reactivity

  Ohnishi, Y., Sakai, M., Nakao, S. & Kitagawa, O., 2011 5 20, In: Organic Letters. 13, p. 2840-2843

  研究成果: Article › 査読

  8 被引用数 (Scopus)
• 2010

  Atropisomeric lactam chemistry: catalytic enantioselective synthesis, application to asymmetric enolate chemistry and synthesis of key intermediates for NET inhibitors

  Takahashi, M., Tanabe, H., Nakamura, T., Kuribara, D., Yamazaki, T. & Kitagawa, O., 2010 1 2, In: Tetrahedron. 66, 1, p. 288-296 9 p.

  研究成果: Article › 査読

  • Lactams
  • palladium(II) acetate
  • Anilides
  • Silica Gel
  • Purification
  46 被引用数 (Scopus)

• Atropisomeric lactam chemistry: catalytic enantioselective synthesis, application to asymmetric enolate chemistry and synthesis of key intermediates for NET inhibitors

  Takahashi, M., Tanabe, H., Nakamura, T., Kuribara, D., Yamazaki, T. & Kitagawa, O., 2010 1 5, In: Tetrahedron. 66, p. 288-296

  研究成果: Article › 査読

  46 被引用数 (Scopus)

• Catalytic enantioselective synthesis of atropisomeric indoles with an N-C chiral axis

  Ototake, N., Morimoto, Y., Mokuya, A., Fukaya, H., Shida, Y. & Kitagawa, O., 2010 6 18, In: Chemistry - A European Journal. 16, 23, p. 6752-6755 4 p.

  研究成果: Article › 査読

  • palladium chloride
  • Indoles
  • 1,3-benzodioxole
  59 被引用数 (Scopus)

• Catalytic Enantioselective Synthesis of Atropisomeric Indoles with an N-C Chiral Axis.

  Ototake, N., Morimoto, Y., Mokuya, A., Fukaya, H., Shida, Y. & Kitagawa, O., 2010 5 13, In: Chem. Eur. J.. 16, p. 6752-6755

  研究成果: Article › 査読

  59 被引用数 (Scopus)
• 2009

  Highly selective stereodivergent synthesis of separable amide rotamers, by using Pd chemistry, and their thermodynamic behavior

  Ototake, N., Nakamura, M., Dobashi, Y., Fukaya, H. & Kitagawa, O., 2009 5 11, In: Chemistry - A European Journal. 15, 20, p. 5090-5095 6 p.

  研究成果: Article › 査読

  • Allylation
  • Anilides
  • Amides
  • Thermodynamics
  • Isomers
  14 被引用数 (Scopus)

• Highly Selective Stereodivergent Synthesis of Separable Amide Rotamers Using Pd Chemistry and Their Thermodynamic Behaviors.

  Ototake, N., Nakamura, M., Dobashi, Y., Fukaya, H. & Kitagawa, O., 2009 5 1, In: Chem. Eur. J.. 15, p. 5090-5095

  研究成果: Article › 査読
• 2008

  Catalytic enantioselective synthesis of key intermediates for NET inhibitors using atropisomeric lactam chemistry

  Kitagawa, O., Kurihara, D., Tanabe, H., Shibuya, T. & Taguchi, T., 2008 1 14, In: Tetrahedron Letters. 49, 3, p. 471-474 4 p.

  研究成果: Article › 査読

  • Alkylation
  • Lactams
  • Hydration
  28 被引用数 (Scopus)

• Stereoselective synthesis of separable amide rotamers using p-allyl-Pd catalyst and their thermodynamic behavior

  Ototake, N., Taguchi, T. & Kitagawa, O., 2008 8 1, In: Tetrahedron Lett.. 49, p. 5458-5460

  研究成果: Article › 査読

• Stereoselective synthesis of separable amide rotamers using π-allyl-Pd catalyst and their thermodynamic behavior

  Ototake, N., Taguchi, T. & Kitagawa, O., 2008 9 15, In: Tetrahedron Letters. 49, 38, p. 5458-5460 3 p.

  研究成果: Article › 査読

  • Allylation
  • Thermodynamics
  • Amides
  • Anilides
  • Catalysts
  9 被引用数 (Scopus)
• 2007

  Highly Enantioselctive Synthesis of Atropisomeric Lactams through Catalytic Asymmetric Buchwald-Hartwig Amination

  Kitagawa, O., Tanabe, H. & Taguchi, T., 2007 8 23, In: Default journal.

  研究成果: Article › 査読
• 2006

  Catalytic asymmetric desymmetrization of meso-diamide derivatives through enantioselective N-allylation with a chiral π-allyl Pd catalyst: Improvement and reversal of the enantioselectivity

  Kitagawa, O., Matsuo, S., Yotsumoto, K. & Taguchi, T., 2006 3 17, In: Journal of Organic Chemistry. 71, 6, p. 2524-2527 4 p.

  研究成果: Article › 査読

  • Allylation
  • Diamide
  • Catalysts
  • Derivatives
  • Diamines
  18 被引用数 (Scopus)

• Catalytic Asymmetyric Desymmetrization of meso-Diamide derivatives through Enantioselective N-Allylation Using Chiral -Allyl Pd Catalyst: Improvement and Reversal of the Enantioselectivity.

  Kitagawa, O., Matsuo, S., Yotsumoto, K. & Taguchi, T., 2006 2 1, In: J. Org. Chem.. 71, p. 2524-2527

  研究成果: Article › 査読