• 393 引用
  • 7 h指数
20082020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 393 引用
  • 7 h指数
  • 20 Article
  • 2 Comment/debate
  • 1 Review article
フィルター
Article
2008
12 引用 (Scopus)
2010

Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme

Nakagawa, K., Hirota, Y., Sawada, N., Yuge, N., Watanabe, M., Uchino, Y., Okuda, N., Shimomura, Y., Suhara, Y. & Okano, T., 2010 11 4, : : Nature. 468, 7320, p. 117-121 5 p.

研究成果: Article

174 引用 (Scopus)
2013

Menadione (vitamin K3) is a catabolic product of oral phylloquinone (vitamin K1) in the intestine and a circulating precursor of tissue menaquinone-4 (vitamin K2) in rats

Hirota, Y., Tsugawa, N., Nakagawa, K., Suhara, Y., Tanaka, K., Uchino, Y., Takeuchi, A., Sawada, N., Kamao, M., Wada, A., Okitsu, T. & Okano, T., 2013 11 15, : : Journal of Biological Chemistry. 288, 46, p. 33071-33080 10 p.

研究成果: Article

57 引用 (Scopus)

The UBIAD1 Prenyltransferase Links Menaquione-4 Synthesis to Cholesterol Metabolic Enzymes

Nickerson, M. L., Bosley, A. D., Weiss, J. S., Kostiha, B. N., Hirota, Y., Brandt, W., Esposito, D., Kinoshita, S., Wessjohann, L., Morham, S. G., Andresson, T., Kruth, H. S., Okano, T. & Dean, M., 2013 2, : : Human Mutation. 34, 2, p. 317-329 13 p.

研究成果: Article

48 引用 (Scopus)
2014

Vitamin K2 biosynthetic enzyme, UBIAD1 is essential for embryonic development of mice

Nakagawa, K., Sawada, N., Hirota, Y., Uchino, Y., Suhara, Y., Hasegawa, T., Amizuka, N., Okamoto, T., Tsugawa, N., Kamao, M., Funahashi, N. & Okano, T., 2014 8 15, : : PLoS ONE. 9, 8, e104078.

研究成果: Article

22 引用 (Scopus)
2015

Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1

Hirota, Y., Nakagawa, K., Sawada, N., Okuda, N., Suhara, Y., Uchino, Y., Kimoto, T., Funahashi, N., Kamao, M., Tsugawa, N. & Okano, T., 2015 4 15, : : PLoS ONE. 10, 4, e0125737.

研究成果: Article

23 引用 (Scopus)

Synthetic Small Molecules Derived from Natural Vitamin K Homologues that Induce Selective Neuronal Differentiation of Neuronal Progenitor Cells

Suhara, Y., Hirota, Y., Hanada, N., Nishina, S., Eguchi, S., Sakane, R., Nakagawa, K., Wada, A., Takahashi, K., Tokiwa, H. & Okano, T., 2015 9 10, : : Journal of Medicinal Chemistry. 58, 17, p. 7088-7092 5 p.

研究成果: Article

5 引用 (Scopus)

YY1 positively regulates human UBIAD1 expression

Funahashi, N., Hirota, Y., Nakagawa, K., Sawada, N., Watanabe, M., Suhara, Y. & Okano, T., 2015 5 1, : : Biochemical and Biophysical Research Communications. 460, 2, p. 238-244 7 p.

研究成果: Article

6 引用 (Scopus)
2017

Flavan 3-ol delays the progression of disuse atrophy induced by hindlimb suspension in mice

Ito, M., Kudo, N., Miyake, Y., Imai, T., Unno, T., Yamashita, Y., Hirota, Y., Ashida, H. & Osakabe, N., 2017 11 1, : : Experimental Gerontology. 98, p. 120-123 4 p.

研究成果: Article

3 引用 (Scopus)

Nongenomic effects of 1α,25-dihydroxyvitamin D3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice

Hirota, Y., Nakagawa, K., Mimatsu, S., Sawada, N., Sakaki, T., Kubodera, N., Kamao, M., Tsugawa, N., Suhara, Y. & Okano, T., 2017 1 29, : : Biochemical and Biophysical Research Communications. 483, 1, p. 359-365 7 p.

研究成果: Article

5 引用 (Scopus)
9 引用 (Scopus)

Synthesis of novel vitamin K derivatives with alkylated phenyl groups introduced at the ω-terminal side chain and evaluation of their neural differentiation activities

Sakane, R., Kimura, K., Hirota, Y., Ishizawa, M., Takagi, Y., Wada, A., Kuwahara, S., Makishima, M. & Suhara, Y., 2017 11 1, : : Bioorganic and Medicinal Chemistry Letters. 27, 21, p. 4881-4884 4 p.

研究成果: Article

4 引用 (Scopus)
2018

Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice

HirotaI, Y., Nakagawa, K., Isomoto, K., Sakaki, T., Kubodera, N., Kamao, M., Osakabe, N., Suhara, Y. & Okano, T., 2018 10, : : PLoS ONE. 13, 10, e0199856.

研究成果: Article

1 引用 (Scopus)

Generation of 1,25-dihydroxyvitamin D3 in Cyp27b1 knockout mice by treatment with 25-hydroxyvitamin D3 rescued their rachitic phenotypes

Nishikawa, M., Yasuda, K., Takamatsu, M., Abe, K., Nakagawa, K., Tsugawa, N., Hirota, Y., Tanaka, K., Yamashita, S., Ikushiro, S., Suda, T., Okano, T. & Sakaki, T., 2018 1 1, (Accepted/In press) : : Journal of Steroid Biochemistry and Molecular Biology.

研究成果: Article

6 引用 (Scopus)
2019

Acylated anthocyanins derived from purple carrot (: Daucus carota L.) induce elevation of blood flow in rat cremaster arteriole

Tsutsumi, A., Horikoshi, Y., Fushimi, T., Saito, A., Koizumi, R., Fujii, Y., Hu, Q. Q., Hirota, Y., Aizawa, K. & Osakabe, N., 2019 3 1, : : Food and Function. 10, 3, p. 1726-1735 10 p.

研究成果: Article

6 引用 (Scopus)
公開
1 引用 (Scopus)

Synthesis and in vitro evaluation of novel liver X receptor agonists based on naphthoquinone derivatives

Nishioka, T., Endo-Umeda, K., Ito, Y., Shimoda, A., Takeuchi, A., Tode, C., Hirota, Y., Osakabe, N., Makishima, M. & Suhara, Y., 2019 11 26, : : Molecules. 24, 23, 4316.

研究成果: Article

公開
2020

Generation of novel genetically modified rats to reveal the molecular mechanisms of vitamin D actions

Nishikawa, M., Yasuda, K., Takamatsu, M., Abe, K., Okamoto, K., Horibe, K., Mano, H., Nakagawa, K., Tsugawa, N., Hirota, Y., Horie, T., Hinoi, E., Okano, T., Ikushiro, S. & Sakaki, T., 2020 12 1, : : Scientific Reports. 10, 1, 5677.

研究成果: Article

公開
公開