Abnormal D-serine metabolism in amyotrophic lateral sclerosis

Medicine & Life Sciences

• Amyotrophic Lateral Sclerosis 70%
• Serine 63%
• D-Amino-Acid Oxidase 39%
• Amyotrophic lateral sclerosis 1 31%
• Motor Neurons 22%
• Neuroglia 20%
• Superoxide Dismutase-1 15%
• Glutamic Acid 10%
• Spinal Cord 9%
• Neurons 7%
• Inclusion Bodies 6%
• Loss of Function Mutation 6%
• Mutation 6%
• Glutamate Receptors 6%
• Enzymes 6%
• N-Methylaspartate 6%
• N-Methyl-D-Aspartate Receptors 5%
• Autophagy 5%
• Neurodegenerative Diseases 5%
• Poisons 4%
• Pathology 3%
• Apoptosis 3%

Chemical Compounds

• D-Serine 100%
• Pharmacological Metabolism 50%
• Mutation 20%
• Cord 20%
• Excitotoxicity 14%
• Acid 11%
• Superoxide 7%
• Toxic 6%