Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats

Seigo Baba; Naomi Osakabe; Midori Natsume; Junji Terao

doi:10.1016/S0891-5849(02)00871-7

Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats

Seigo Baba, Naomi Osakabe, Midori Natsume, Junji Terao

研究成果: Article

190 引用（Scopus）

抜粋

We evaluated the bioavailability and plasma antioxidative activity after administration of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats. After procyanidin B2 administration, procyanidin B2 is absorbed and excreted in urine, and a portion of the PB2 is degraded to (-)-epicatechin and to the metabolized conjugated and/or methylated (-)-epicatechin internally in the rat. Moreover, PB2 reduces the accumulation of lipid peroxide in plasma oxidized by copper ions.

元の言語	English
ページ（範囲）	142-148
ページ数	7
ジャーナル	Free Radical Biology and Medicine
巻	33
発行部数	1
DOI	https://doi.org/10.1016/S0891-5849(02)00871-7
出版物ステータス	Published - 2002 7 1

フィンガープリント

ASJC Scopus subject areas

Biochemistry
Physiology (medical)

これを引用

Baba, S., Osakabe, N., Natsume, M., & Terao, J. (2002). Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats. Free Radical Biology and Medicine, 33(1), 142-148. https://doi.org/10.1016/S0891-5849(02)00871-7

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abstract = "We evaluated the bioavailability and plasma antioxidative activity after administration of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats. After procyanidin B2 administration, procyanidin B2 is absorbed and excreted in urine, and a portion of the PB2 is degraded to (-)-epicatechin and to the metabolized conjugated and/or methylated (-)-epicatechin internally in the rat. Moreover, PB2 reduces the accumulation of lipid peroxide in plasma oxidized by copper ions.",

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AU - Natsume, Midori

AU - Terao, Junji

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KW - (-)-Epicatechin

KW - Absorption

KW - Antioxidant

KW - Conjugation

KW - Degradation

KW - Free radicals

KW - Methylation

KW - Procyanidin B2

KW - Rats

KW - Urinary excretion

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文献にアクセス

10.1016/S0891-5849(02)00871-7