Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats

Seigo Baba, Naomi Osakabe, Midori Natsume, Junji Terao

研究成果: Article

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We evaluated the bioavailability and plasma antioxidative activity after administration of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats. After procyanidin B2 administration, procyanidin B2 is absorbed and excreted in urine, and a portion of the PB2 is degraded to (-)-epicatechin and to the metabolized conjugated and/or methylated (-)-epicatechin internally in the rat. Moreover, PB2 reduces the accumulation of lipid peroxide in plasma oxidized by copper ions.

元の言語English
ページ(範囲)142-148
ページ数7
ジャーナルFree Radical Biology and Medicine
33
発行部数1
DOI
出版物ステータスPublished - 2002 7 1

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ASJC Scopus subject areas

  • Biochemistry
  • Physiology (medical)

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