This paper proposes active RFID tag drive by a thermoelectric conversion element by using temperature difference between outside air and human skin. In recent years, energy harvesting techniques have been attracting attention. Powers saving sensors driven by energy harvesting techniques are expected to eliminate maintenance such as battery replacement. Therefore, in this study, the active RFID tags were driven by the thermoelectric conversion elements by using temperature difference. Furthermore, the performance of the thermoelectric conversion elements was evaluated and compared to commercial Lithium battery. As a result, active RFID tag driven by the thermoelectric conversion element has proved to have the same performance as active RFID tag driven by Lithium battery. Therefore, it was confirmed that the driving of the active RFID tag using a thermoelectric conversion element is feasible.