Anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using HFIP as a solvent

Toshiki Tajima, Hitoshi Kurihara, Shoichi Shimizu, Hiroyuki Tateno

研究成果: Article

5 引用 (Scopus)

抄録

We have demonstrated anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using 1,1,1,3,3,3- hexafluoroisopropanol (HFIP) as a solvent. In the two-step transformation, HFIP acted as a nucleophile in the presence of solid-supported bases, while it acted as an inert solvent in the absence of solidsupported bases. This enabled us to conduct anodic alkoxylation of lactams and subsequent C-C bond forming reactions without replacing the solvent.

元の言語English
ページ(範囲)353-355
ページ数3
ジャーナルElectrochemistry
81
発行部数5
DOI
出版物ステータスPublished - 2013 5

Fingerprint

Lactams
Nucleophiles
Carbon
hexafluoroisopropanol

ASJC Scopus subject areas

  • Electrochemistry

これを引用

Anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using HFIP as a solvent. / Tajima, Toshiki; Kurihara, Hitoshi; Shimizu, Shoichi; Tateno, Hiroyuki.

:: Electrochemistry, 巻 81, 番号 5, 05.2013, p. 353-355.

研究成果: Article

Tajima, Toshiki ; Kurihara, Hitoshi ; Shimizu, Shoichi ; Tateno, Hiroyuki. / Anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using HFIP as a solvent. :: Electrochemistry. 2013 ; 巻 81, 番号 5. pp. 353-355.
@article{9ddee57c909e4397a84371110052d785,
title = "Anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using HFIP as a solvent",
abstract = "We have demonstrated anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using 1,1,1,3,3,3- hexafluoroisopropanol (HFIP) as a solvent. In the two-step transformation, HFIP acted as a nucleophile in the presence of solid-supported bases, while it acted as an inert solvent in the absence of solidsupported bases. This enabled us to conduct anodic alkoxylation of lactams and subsequent C-C bond forming reactions without replacing the solvent.",
keywords = "Anodic alkoxylation, Carbon-carbon bond forming reactions, Hfip, Solid-supported bases",
author = "Toshiki Tajima and Hitoshi Kurihara and Shoichi Shimizu and Hiroyuki Tateno",
year = "2013",
month = "5",
doi = "10.5796/electrochemistry.81.353",
language = "English",
volume = "81",
pages = "353--355",
journal = "Electrochemistry",
issn = "1344-3542",
publisher = "Electrochemical Society of Japan",
number = "5",

}

TY - JOUR

T1 - Anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using HFIP as a solvent

AU - Tajima, Toshiki

AU - Kurihara, Hitoshi

AU - Shimizu, Shoichi

AU - Tateno, Hiroyuki

PY - 2013/5

Y1 - 2013/5

N2 - We have demonstrated anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using 1,1,1,3,3,3- hexafluoroisopropanol (HFIP) as a solvent. In the two-step transformation, HFIP acted as a nucleophile in the presence of solid-supported bases, while it acted as an inert solvent in the absence of solidsupported bases. This enabled us to conduct anodic alkoxylation of lactams and subsequent C-C bond forming reactions without replacing the solvent.

AB - We have demonstrated anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using 1,1,1,3,3,3- hexafluoroisopropanol (HFIP) as a solvent. In the two-step transformation, HFIP acted as a nucleophile in the presence of solid-supported bases, while it acted as an inert solvent in the absence of solidsupported bases. This enabled us to conduct anodic alkoxylation of lactams and subsequent C-C bond forming reactions without replacing the solvent.

KW - Anodic alkoxylation

KW - Carbon-carbon bond forming reactions

KW - Hfip

KW - Solid-supported bases

UR - http://www.scopus.com/inward/record.url?scp=84878967670&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878967670&partnerID=8YFLogxK

U2 - 10.5796/electrochemistry.81.353

DO - 10.5796/electrochemistry.81.353

M3 - Article

AN - SCOPUS:84878967670

VL - 81

SP - 353

EP - 355

JO - Electrochemistry

JF - Electrochemistry

SN - 1344-3542

IS - 5

ER -